SCHEMBL455574

SCHEMBL455574

O=C(O)C1=C(c2ccccc2)C2=NC1=CC1=NC(=CC3=NC(=CC4=NC(=C2)C=C4)C=C3)C=C1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 1/20 0.35
▸ FGFR2 P21802 1/20 0.35
▸ FGFR4 P22455 1/20 0.35
▸ FGFR3 P22607 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27845971 0.90 FGFR1 (0.38) FGFR1FGFR2FGFR4FGFR3
SCHEMBL27841889 0.86 FGFR1 (0.41) FGFR1FGFR2FGFR4FGFR3
SCHEMBL1063742 0.86 — —
SCHEMBL226836 0.83 — —
SCHEMBL8846964 0.82 — —
SCHEMBL11314685 0.81 — —
SCHEMBL6291667 0.81 — —
SCHEMBL28107586 0.79 — —
SCHEMBL9059026 0.78 — —
SCHEMBL9510590 0.77 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12461102-B2 Pristine graphene based biosensor for biomarker detection and related core particles, materials compositions methods and systems HAWKEYE BIO, LIMITED (IE) 2025-11-04 — — US claimed
WO-2024010609-A1 PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS HAWKEYE BIO, LIMITED (IE) 2024-01-11 — — WO claimed
EP-4271651-A1 PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS HAWKEYE BIO, LIMITED (IE) 2023-11-08 — — EP claimed
WO-2022147171-A1 PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS HAWKEYE BIO, LIMITED (US) 2022-07-07 — — WO claimed
WO-2016018798-A1 NANOSENSORS FOR DETECTING ENZYMATIC ACTIVITY IN DAIRY PRODUCTION KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2016-02-04 — — WO claimed
US-8969027-B2 Protease assay KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2015-03-03 — — US claimed
EP-2473620-A2 MRI AND OPTICAL ASSAYS FOR PROTEASES Kansas State University Research Foundation (US) 2012-07-11 — — EP claimed
JP-2011517934-A — — 2011-06-23 — — JP claimed
WO-2011028698-A2 MRI AND OPTICAL ASSAYS FOR PROTEASES KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-03-10 — — WO claimed
US-20110014125-A1 PROTEASE ASSAY KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-01-20 — — US claimed
EP-2260108-A2 PROTEASE ASSAY Kansas State University Research Foundation (US) 2010-12-15 — — EP claimed
WO-2009111470-A2 PROTEASE ASSAY KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2009-09-11 — — WO claimed
US-12461102-B2 Pristine graphene based biosensor for biomarker detection and related core particles, materials compositions methods and systems HAWKEYE BIO, LIMITED (IE) 2025-11-04 — — US disclosed
EP-4271651-B1 PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS HAWKEYE BIO LTD (IE) 2024-10-23 — — EP disclosed
US-11965881-B2 Nanosensors and methods for detection of biological markers KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2024-04-23 — — US disclosed
US-20240125800-A1 NANOSENSORS FOR RAPID IDENTIFICATION OF LUNG CONDITIONS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-04-18 — — US disclosed
WO-2009111470-A2 PROTEASE ASSAY KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2009-09-11 — — WO disclosed
CN-101516319-A Dental compositions including organogelators, products, and methods 3M INNOVATIVE PROPERTIES CO (US) 2009-08-26 — — CN disclosed
EP-0070686-B1 NON-RADIATIVE ENERGY TRANSFER IMMUNOCHEMICAL TECHNIQUE AMOCO CORPORATION (US) 1985-10-02 — — EP disclosed
EP-0070686-A2 Non-radiative energy transfer immunochemical technique AMOCO CORPORATION (US) 1983-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110014125-A1 PROTEASE ASSAY PREP, TMPRSS15, PRSS3 FGFR1 3133/4885FGFR2 3512/4885FGFR4 2613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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