Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 2/20 | 0.42 |
| ▸ | CPT1A | P50416 | 2/20 | 0.42 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555806 | 0.90 | MEN1 (0.51) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL4555807 | 0.88 | KMT2A (0.50) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL4556081 | 0.83 | AAK1 (0.47) | MEN1KMT2APKMALDH1A1NR1H4 | |
| SCHEMBL4556085 | 0.82 | DHPS (0.52) | MEN1KMT2APKMALDH1A1POLB | |
| SCHEMBL4556124 | 0.82 | CPT1A (0.44) | MEN1KMT2APKMALDH1A1POLB | |
| SCHEMBL2814428 | 0.81 | KMT2A (0.60) | MEN1KMT2APKMALDH1A1POLB | |
| SCHEMBL4556122 | 0.80 | CPT1A (0.44) | MEN1KMT2APKMALDH1A1POLB | |
| SCHEMBL4439131 | 0.79 | HPSE (0.49) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL4439125 | 0.77 | HPSE (0.49) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL4556044 | 0.77 | NR1H4 (0.49) | MEN1KMT2APKMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |