Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556042 | 0.89 | ESR1 (0.49) | NR1H4EPHX2ESR1PKMMEN1 | |
| SCHEMBL4556043 | 0.86 | ESR1 (0.50) | NR1H4ESR1PKMMEN1KMT2A | |
| SCHEMBL4556271 | 0.85 | PKM (0.46) | NR1H4EPHX2PKMMEN1KMT2A | |
| SCHEMBL2814428 | 0.84 | KMT2A (0.60) | NR1H4PKMMEN1KMT2ANPC1 | |
| SCHEMBL4556085 | 0.83 | DHPS (0.52) | NR1H4PKMMEN1KMT2ANPC1 | |
| SCHEMBL4446512 | 0.80 | PKM (0.51) | NR1H4PKMMEN1KMT2ANPC1 | |
| SCHEMBL4555552 | 0.79 | SMN1; SMN2 (0.57) | NR1H4EPHX2PKMMEN1KMT2A | |
| SCHEMBL4556337 | 0.78 | NPC1 (0.56) | NR1H4PKMMEN1KMT2ANPC1 | |
| SCHEMBL4438564 | 0.78 | PKM (0.46) | NR1H4PKMMEN1KMT2ANPC1 | |
| SCHEMBL27776090 | 0.78 | IMPDH2 (0.51) | NR1H4PKMMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |