Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555840 | 0.84 | EPHX2 (0.41) | PPARGHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL4555966 | 0.81 | EPHX2 (0.39) | PPARGHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL2820070 | 0.75 | ALDH1A1 (0.48) | PPARGHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL4556270 | 0.67 | MEN1 (0.45) | SMN1; SMN2TP53 | |
| SCHEMBL24479851 | 0.62 | PPARG (0.56) | PPARGSMN1; SMN2TP53 | |
| SCHEMBL27796830 | 0.61 | MAPT (0.46) | SMN1; SMN2TP53POLB | |
| SCHEMBL3349836 | 0.61 | CYP1A2 (0.56) | HDAC3HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL4556271 | 0.60 | PKM (0.46) | SMN1; SMN2TP53POLB | |
| SCHEMBL25120829 | 0.59 | KDR (0.37) | AR | |
| SCHEMBL24479857 | 0.58 | HPGD (0.59) | TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |