Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CALCA | P06881 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826035 | 0.80 | TP53 (0.48) | SMN1; SMN2ERCC1FEN1ERCC4KCNE1 | |
| SCHEMBL1876737 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2ERCC1FEN1ERCC4KCNE1 | |
| SCHEMBL823326 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2ERCC1FEN1ERCC4KCNE1 | |
| SCHEMBL4555867 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2ERCC1FEN1ERCC4KCNE1 | |
| SCHEMBL823318 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2ERCC1FEN1ERCC4KCNE1 | |
| SCHEMBL823370 | 0.75 | KCNE1 (0.49) | SMN1; SMN2ERCC1FEN1ERCC4KCNE1 | |
| SCHEMBL823513 | 0.75 | ERCC1 (0.48) | SMN1; SMN2ERCC1FEN1ERCC4KCNE1 | |
| SCHEMBL823340 | 0.75 | KCNE1 (0.47) | SMN1; SMN2ERCC1FEN1ERCC4KCNE1 | |
| SCHEMBL823368 | 0.75 | CYP2C9 (0.55) | SMN1; SMN2ERCC1FEN1ERCC4KCNE1 | |
| SCHEMBL823459 | 0.74 | MEN1 (0.58) | SMN1; SMN2ERCC1FEN1ERCC4KCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114903-A1 | BICYCLIC PYRIMIDINONES AND USES THEREOF | Avexa Limited (AU) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008077188-A1 | BICYCLIC PYRIMIDINONES AND USES THEREOF | AVEXA LIMITED (AU) | 2008-07-03 | — | — | WO | disclosed |