Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL635622 | 0.97 | ALDH1A1 (0.54) | SRCALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL3851835 | 0.88 | SRC (0.63) | SRCALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL29750488 | 0.80 | ALDH1A1 (0.63) | SRCALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL636591 | 0.80 | ALDH1A1 (0.63) | SRCALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL4556262 | 0.79 | ALDH1A1 (0.54) | SRCALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL2817952 | 0.78 | ALDH1A1 (0.56) | SRCALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL1276592 | 0.76 | ALDH1A1 (0.79) | SRCALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL30972130 | 0.76 | ALDH1A1 (0.79) | SRCALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL12283515 | 0.74 | SRC (0.51) | SRCALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL1300080 | 0.74 | HPGD (0.62) | SRCHPGDMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035369-A1 | THERAPEUTIC COMPOUNDS | Fibrotech Therapeutics PTY LTD (AU) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008003141-A1 | THERAPEUTIC COMPOUNDS | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2008-01-10 | — | — | WO | disclosed |