Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817952 | 0.98 | ALDH1A1 (0.56) | ALDH1A1HPGDHTTSMN1; SMN2SRC | |
| SCHEMBL4555928 | 0.79 | SRC (0.57) | ALDH1A1HPGDHTTSMN1; SMN2SRC | |
| SCHEMBL11779563 | 0.79 | SRC (0.49) | ALDH1A1HPGDHTTSMN1; SMN2SRC | |
| SCHEMBL3851835 | 0.78 | SRC (0.63) | ALDH1A1HPGDHTTSMN1; SMN2SRC | |
| SCHEMBL7358840 | 0.78 | MAPT (0.50) | ALDH1A1HPGDHTTSMN1; SMN2KMT2A | |
| SCHEMBL30972130 | 0.78 | ALDH1A1 (0.79) | ALDH1A1HPGDHTTSMN1; SMN2SRC | |
| SCHEMBL1276592 | 0.78 | ALDH1A1 (0.79) | ALDH1A1HPGDHTTSMN1; SMN2SRC | |
| SCHEMBL5302703 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2SRC | |
| SCHEMBL635622 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDHTTSMN1; SMN2SRC | |
| SCHEMBL8751776 | 0.76 | HPGD (0.38) | ALDH1A1HPGDPTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035369-A1 | THERAPEUTIC COMPOUNDS | Fibrotech Therapeutics PTY LTD (AU) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008003141-A1 | THERAPEUTIC COMPOUNDS | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2008-01-10 | — | — | WO | disclosed |