Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556081 | 0.88 | AAK1 (0.47) | AAK1ALDH1A1NR1H4CLK1DYRK1A | |
| SCHEMBL4556079 | 0.84 | AAK1 (0.53) | AAK1ALDH1A1NR1H4CLK1DYRK1A | |
| SCHEMBL4564334 | 0.83 | ROCK2 (0.45) | ALDH1A1NR1H4MAPTTP53SMN1; SMN2 | |
| SCHEMBL4555807 | 0.83 | KMT2A (0.50) | ALDH1A1NR1H4MAPTTP53SMN1; SMN2 | |
| SCHEMBL2818006 | 0.82 | MEN1 (0.53) | NR1H4MAPTMEN1KMT2APKM | |
| SCHEMBL2814955 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MAPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL4563838 | 0.80 | NR1H4 (0.45) | ALDH1A1NR1H4MAPTTP53SMN1; SMN2 | |
| SCHEMBL4438562 | 0.78 | KMT2A (0.45) | ALDH1A1NR1H4MAPTTP53SMN1; SMN2 | |
| SCHEMBL4556270 | 0.78 | MEN1 (0.45) | ALDH1A1NR1H4MAPTTP53SMN1; SMN2 | |
| SCHEMBL2815122 | 0.78 | KMT2A (0.57) | ALDH1A1NR1H4MAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | claimed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | claimed |