Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.95 |
| ▸ | MMP2 | P08253 | 1/20 | 0.95 |
| ▸ | MMP9 | P14780 | 1/20 | 0.95 |
| ▸ | MMP13 | P45452 | 1/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050511 | 1.00 | MMP1 (0.95) | MMP1MMP2MMP9MMP13 | |
| SCHEMBL4050506 | 1.00 | MMP1 (0.95) | MMP1MMP2MMP9MMP13 | |
| SCHEMBL4053399 | 0.98 | MMP2 (1.00) | MMP1MMP2MMP9MMP13 | |
| SCHEMBL4053389 | 0.98 | MMP2 (1.00) | MMP1MMP2MMP9MMP13 | |
| SCHEMBL4556600 | 0.98 | MMP2 (1.00) | MMP1MMP2MMP9MMP13 | |
| SCHEMBL4050802 | 0.88 | MMP1 (0.74) | MMP1MMP2MMP9MMP13 | |
| SCHEMBL4556617 | 0.88 | MMP1 (0.74) | MMP1MMP2MMP9MMP13 | |
| SCHEMBL4050807 | 0.88 | MMP1 (0.74) | MMP1MMP2MMP9MMP13 | |
| SCHEMBL4049378 | 0.85 | MMP2 (0.78) | MMP1MMP2MMP9MMP13 | |
| SCHEMBL6232271 | 0.82 | MMP1 (0.67) | MMP1MMP2MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397137-B1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | EP | claimed |