SCHEMBL74194

SCHEMBL74194

Brc1ccc(-c2ccc(I)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
MAPK1 P28482 3/20 0.55
CYP2A6 P11509 1/20 0.50
APP P05067 1/20 0.46
CA12 O43570 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
ALOX15 P16050 2/20 0.38
NPC1 O15118 1/20 0.38
NFKB1 P19838 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CNR1 P21554 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
GAA P10253 3/20 0.34
METAP2 P50579 2/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10356669 1.00 ALDH1A1 (0.55) ALDH1A1MAPK1CYP2A6APPCA12
SCHEMBL24146 0.90
SCHEMBL8068361 0.90 CYP2A6 (0.61) ALDH1A1MAPK1CYP2A6APPCA2
SCHEMBL455656 0.90 CYP2A6 (0.61) ALDH1A1MAPK1CYP2A6APPCA2
Water SCHEMBL27920757 0.87 CYP2A6 (0.57) ALDH1A1MAPK1CYP2A6APPCA2
SCHEMBL28222110 0.87
Fluoride SCHEMBL5504537 0.84 CYP2A6 (0.53) ALDH1A1MAPK1CYP2A6APPCA2
SCHEMBL68094 0.83 ALDH1A1 (0.73) ALDH1A1MAPK1CYP2A6CA12CA2
SCHEMBL1673427 0.83 ALDH1A1 (0.73) ALDH1A1MAPK1CYP2A6CA12CA2
SCHEMBL75931 0.83 METAP2 (0.42) ALDH1A1APPCA2TDP1METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 773 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504559-B Novel pure organic multiple luminophor based on aryl carbazole and preparation method thereof 天津大学 2025-05-23 CN claimed
CN-119504559-A Novel pure organic multiple luminophor based on aryl carbazole and preparation method thereof 天津大学 2025-02-25 CN claimed
CN-115073420-A Preparation method of 2-phenylbenzothiophene derivative 陕西维世诺新材料有限公司 2022-09-20 CN claimed
US-12628546-B2 Polymer and organic light-emitting diode using same LG CHEM, LTD. (KR) 2026-05-12 US disclosed
EP-4141041-B1 A POLYMER, A COMPOSITION, AND AN ELECTROLUMINESCENCE DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2026-04-22 EP disclosed
EP-4063466-B1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING SAME SAMSUNG SDI CO LTD (KR) 2026-04-01 EP disclosed
EP-3762388-B1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2026-02-25 EP disclosed
EP-4678632-A1 METHOD FOR PRODUCING ARYL COMPOUND CONTAINING TRITYLSULFANYL GROUP AGC Inc. (JP) 2026-01-14 EP disclosed
US-20250346557-A1 METHOD FOR PRODUCING ARYL COMPOUND CONTAINING TRITYLSULFANYL GROUP AGC Inc. (JP) 2025-11-13 US disclosed
US-12421219-B2 Compound for organic electronic element, organic electronic element using same, and electronic device comprising same DUK SAN NEOLUX CO., LTD. (KR) 2025-09-23 US disclosed
US-20250294961-A1 Polymer and Organic Light-Emitting Device Using Same LG CHEM, LTD. (KR) 2025-09-18 US disclosed
US-6994941-B2 comprises bis(2,4-dimethylphenyl)amine as charge transfer compound; improved wear/scratch resistance and stability CANON KABUSHIKI KAISHA (JP) 2006-02-07 US disclosed
US-20050208402-A1 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2005-09-22 US disclosed
US-20050100805-A1 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2005-05-12 US disclosed
EP-1394617-A2 Electrophotographic Photosensitive Member, Process Cartridge and Electrophotographic Apparatus CANON KABUSHIKI KAISHA (JP) 2004-03-03 EP disclosed
EP-0827367-A2 Electroluminescent devices XEROX CORPORATION (US) 1998-03-04 EP disclosed
EP-0391212-B1 Process for preparing bifunctional Z-stilbene compounds, new bifunctional Z-stilbene compounds and their use for preparing polymers BAYER AG (DE) 1994-05-25 EP disclosed
US-5136013-A Polyesters BAYER AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed
US-5068300-A BIFUNCTIONAL STILBENE COMPOUNDS CONTAINING AT LEAST ONE Z-CONFIGURATED STILBENE GROUP, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed
EP-0391212-A2 Process for preparing bifunctional Z-stilbene compounds, new bifunctional Z-stilbene compounds and their use for preparing polymers BAYER AG (DE) 1990-10-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12628546-B2 Polymer and organic light-emitting diode using same CCNE2, CCNL2, CCNB1 ALDH1A1 225/4885MAPK1 1927/4885CYP2A6 648/4885
US-12421219-B2 Compound for organic electronic element, organic electronic element using same, and electronic device comprising same OR51E2, ETV6, OR10J3 ALDH1A1 1356/4885MAPK1 3780/4885CYP2A6 1758/4885
US-20250346557-A1 METHOD FOR PRODUCING ARYL COMPOUND CONTAINING TRITYLSULFANYL GROUP STS, TST, CYP3A5 ALDH1A1 358/4885MAPK1 1514/4885CYP2A6 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.