Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 9/20 | 0.54 |
| ▸ | MMP12 | P39900 | 2/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059420 | 1.00 | ADAM17 (0.54) | ADAM17MMP12MMP13 | |
| SCHEMBL4059425 | 1.00 | ADAM17 (0.54) | ADAM17MMP12MMP13 | |
| SCHEMBL4057254 | 0.92 | MMP12 (0.54) | ADAM17MMP12MMP13 | |
| SCHEMBL4057259 | 0.92 | MMP12 (0.54) | ADAM17MMP12MMP13 | |
| SCHEMBL4052468 | 0.89 | MMP12 (0.67) | ADAM17MMP12MMP13 | |
| SCHEMBL4052465 | 0.89 | MMP12 (0.67) | ADAM17MMP12MMP13 | |
| SCHEMBL4057319 | 0.89 | MMP12 (0.58) | ADAM17MMP12MMP13 | |
| SCHEMBL4057313 | 0.89 | MMP12 (0.58) | ADAM17MMP12MMP13 | |
| SCHEMBL4442445 | 0.88 | ADAM17 (0.63) | ADAM17MMP12MMP13 | |
| SCHEMBL4441976 | 0.88 | ADAM17 (0.63) | ADAM17MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397137-B1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | EP | claimed |