Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 5/20 | 0.69 |
| ▸ | MMP1 | P03956 | 1/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.64 |
| ▸ | MMP9 | P14780 | 1/20 | 0.64 |
| ▸ | MMP13 | P45452 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053925 | 1.00 | ADAM17 (0.69) | ADAM17MMP1MMP2MMP9MMP13 | |
| SCHEMBL4053921 | 1.00 | ADAM17 (0.69) | ADAM17MMP1MMP2MMP9MMP13 | |
| SCHEMBL4057124 | 0.98 | MMP1 (0.67) | ADAM17MMP1MMP2MMP9MMP13 | |
| SCHEMBL4057122 | 0.98 | MMP1 (0.67) | ADAM17MMP1MMP2MMP9MMP13 | |
| SCHEMBL4563622 | 0.98 | MMP1 (0.67) | ADAM17MMP1MMP2MMP9MMP13 | |
| SCHEMBL4049537 | 0.88 | ADAM17 (0.68) | ADAM17MMP1MMP2MMP9MMP13 | |
| SCHEMBL4049542 | 0.88 | ADAM17 (0.68) | ADAM17MMP1MMP2MMP9MMP13 | |
| SCHEMBL4052488 | 0.87 | ADAM17 (0.64) | ADAM17MMP1MMP2MMP9MMP13 | |
| SCHEMBL4052492 | 0.87 | ADAM17 (0.64) | ADAM17MMP1MMP2MMP9MMP13 | |
| SCHEMBL4052634 | 0.87 | MMP1 (0.65) | ADAM17MMP1MMP2MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397137-B1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | EP | claimed |