SCHEMBL4556620

SCHEMBL4556620

FC(F)(F)Cc1ncc[nH]1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.52
TAAR1 Q96RJ0 9/20 0.49
ALOX15 P16050 1/20 0.45
TERT O14746 1/20 0.41
TBXAS1 P24557 2/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
CYP2D6 P10635 1/20 0.36
TSHR P16473 1/20 0.36
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16673143 0.81 FDPS (0.55) FDPSTAAR1ALOX15TERTTBXAS1
SCHEMBL1706035 0.78 TBXAS1 (0.47) FDPSTAAR1ALOX15TERTTBXAS1
SCHEMBL8820621 0.77 FDPS (0.52) FDPSTAAR1ALOX15TERTTBXAS1
SCHEMBL3074784 0.77 FDPS (0.61) FDPSTAAR1ALOX15TERTTBXAS1
SCHEMBL2622405 0.77 FDPS (0.52) FDPSTAAR1ALOX15TERTTBXAS1
SCHEMBL3077019 0.77 FDPS (0.52) FDPSTAAR1ALOX15TERTTBXAS1
SCHEMBL4051225 0.75 TBXAS1 (0.49) FDPSTAAR1ALOX15TERTTBXAS1
SCHEMBL22648576 0.74 FDPS (0.49) FDPSTAAR1ALOX15TERTTBXAS1
SCHEMBL3295265 0.73
SCHEMBL5897424 0.72 TBXAS1 (0.54) FDPSTAAR1ALOX15TERTTBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116583521-A Imidazopyridazine derivatives as IL-17 modulators UCB生物制药有限责任公司 2023-08-11 CN disclosed
CN-102119157-A Tricyclic 2,4-diamino-L,3,5-triazine derivatives useful for the treatment of cancer and myeloproliferative disorders ASTRAZENECA AB 2011-07-06 CN disclosed
US-7534509-B2 Ambient-temperature molten salts and process for producing the same TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-20060094882-A1 Ambient-temperature molten salts and process for producing the same TOYOTA JIDOSHA KABUSHIKI KAISHA 2006-05-04 US disclosed
CN-1093535-C Imidazole derivative SHIONOGI & CO (JP) 2002-10-30 CN disclosed
CN-1158609-A Imidazole derivative SHIONOGI & CO (JP) 1997-09-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094882-A1 Ambient-temperature molten salts and process for producing the same AFF1, AFF2, AFF4 FDPS 605/4885TAAR1 258/4885ALOX15 2680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.