SCHEMBL4556685

SCHEMBL4556685

CN1C(=O)c2ccc(C(c3ccc4c(c3)C(=O)NC4=O)(C(F)(F)F)C(F)(F)F)cc2C1=O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 4/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HPGD P15428 2/20 0.41
MAPK1 P28482 1/20 0.41
NR1H3 Q13133 2/20 0.40
NR1H2 P55055 1/20 0.40
ALOX15 P16050 1/20 0.39
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
APP P05067 6/20 0.38
PPOX P50336 1/20 0.38
TDP2 O95551 1/20 0.36
POLB P06746 1/20 0.35
GRM5 P41594 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549126 0.91 ALDH1A1 (0.47) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL9550326 0.87 PPOX (0.47) HSD17B10MEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL24380219 0.87 KDM4E (0.38) ALDH1A1HSD17B10MEN1KMT2ANR1H3
SCHEMBL27363856 0.87 ALDH1A1 (0.40) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL12310248 0.84 ALDH1A1 (0.48) ALDH1A1HSD17B10MEN1KMT2AHPGD
SCHEMBL24380223 0.84 KDM4E (0.37) ALDH1A1HSD17B10MEN1KMT2AHPGD
SCHEMBL24938190 0.84 ALDH1A1 (0.41) ALDH1A1HSD17B10MEN1KMT2AHPGD
SCHEMBL25688434 0.82 ANPEP (0.39) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL18726681 0.82 KDM4E (0.35) ALDH1A1HSD17B10MEN1KMT2AHPGD
SCHEMBL15233564 0.81 ALDH1A1 (0.47) ALDH1A1HSD17B10MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218127-A1 CROWN ETHER-CONTAINING POLYMERS SAUDI ARABIAN OIL COMPANY (SA) 2024-07-04 US disclosed
EP-3576863-B1 POLYIMIDE BLENDS, METHODS OF MAKING EACH AND METHODS OF USE UNIV KING ABDULLAH SCI & TECH (SA) 2020-10-07 EP disclosed
US-8493527-B2 Liquid crystal panel and liquid crystal display apparatus NITTO DENKO CORPORATION (JP) 2013-07-23 US disclosed
US-8279378-B2 Producing method for lengthwise optical laminate and liquid crystal panel NITTO DENKO CORPORATION (JP) 2012-10-02 US disclosed
US-8174646-B2 Liquid crystal panel and liquid crystal display NITTO DENKO CORPORATION (JP) 2012-05-08 US disclosed
US-8021572-B2 Optical laminate, polarizing plate, image display, and process for producing an optical laminate NITTO DENKO CORPORATION (JP) 2011-09-20 US disclosed
US-7812901-B2 Liquid crystal panel and liquid crystal display apparatus NITTO DENKO CORPORATION (JP) 2010-10-12 US disclosed
US-20100141873-A1 LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY APPARATUS NITTO DENKO CORPORATION (JP) 2010-06-10 US disclosed
US-20100073608-A1 PRODUCING METHOD FOR LENGTHWISE OPTICAL LAMINATE AND LIQUID CRYSTAL PANEL NITTO DENKO CORPORATION (JP) 2010-03-25 US disclosed
US-20100067112-A1 OPTICAL LAMINATE, POLARIZING PLATE, IMAGE DISPLAY, AND PROCESS FOR PRODUCING AN OPTICAL LAMINATE NITTO DENKO CORPORATION (JP) 2010-03-18 US disclosed
US-20100060831-A1 LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY NITTO DENKO CORPORATION (JP) 2010-03-11 US disclosed
US-7643118-B2 Liquid crystal panel and liquid crystal display device NITTO DENKO CORPORATION (JP) 2010-01-05 US disclosed
US-20090316086-A1 LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY APPARATUS NITTO DENKO CORPORATION (JP) 2009-12-24 US disclosed
US-7582722-B1 Phenylethynylbenzophenone-endcapped hyperbranched poly(arylene-ether-ketone-imides) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2009-09-01 US disclosed
US-20090109385-A1 LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2009-04-30 US disclosed