Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL10422544 | 0.96 | — | — | |
| Propylene Glycol SCHEMBL8031321 | 0.96 | — | — | |
| Propylene Glycol SCHEMBL669503 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL7522896 | 0.91 | TDP1 (1.00) | — | |
| Propylene Glycol SCHEMBL55583 | 0.91 | — | — | |
| Propylene Glycol SCHEMBL161401 | 0.91 | TDP1 (1.00) | — | |
| Propylene Glycol SCHEMBL28578 | 0.91 | — | — | |
| Propylene Glycol SCHEMBL724028 | 0.91 | TDP1 (1.00) | — | |
| Propylene Glycol SCHEMBL3535 | 0.91 | — | — | |
| Propylene Glycol SCHEMBL15864609 | 0.91 | TDP1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971372-B1 | HYDROPHOBIC CORE CARRIER COMPOSITIONS FOR DELIVERY OF THERAPEUTIC AGENTS, METHODS OF MAKING AND USING THE SAME | PHARMAIN CORP (US) | 2018-11-14 | — | — | EP | disclosed |
| US-20170368190-A1 | Hydrophobic Core Carrier Compositions for Delivery of Therapeutic Agents, Methods of Making and Using the Same | PHARMAIN CORPORATION (US) | 2017-12-28 | — | — | US | disclosed |
| US-9737615-B2 | Hydrophobic core carrier compositions for delivery of therapeutic agents, methods of making and using the same | PharmalN Corporation (US) | 2017-08-22 | — | — | US | disclosed |
| US-20140154203-A1 | Hydrophobic Core Carrier Compositions for Delivery of Therapeutic Agents, Methods of Making and Using The Same | PHARMAIN CORPORATION (US) | 2014-06-05 | — | — | US | disclosed |
| US-8563527-B2 | Oligonucleotide core carrier compositions for delivery of nucleic acid-containing therapeutic agents, methods of making and using the same | PHARMAIN CORPORATION (US) | 2013-10-22 | — | — | US | disclosed |
| CN-101365490-B | Hydrophobic core carrier compositions for delivery of therapeutic agents, methods of making and using the same | PHARMAIN CORP | 2012-11-28 | — | — | CN | disclosed |
| US-20090053169-A1 | Oligonucleotide Core Carrier Compositions for Delivery of Nucleic Acid-Containing Therapeutic Agents, Methods of Making and Using the Same | PHARMAIN CORPORATION (US) | 2009-02-26 | — | — | US | disclosed |
| CN-101365490-A | Hydrophobic core carrier compositions for delivery of therapeutic agents, methods of making and using the same | PHARMAIN CORP (US) | 2009-02-11 | — | — | CN | disclosed |
| EP-1971372-A2 | HYDROPHOBIC CORE CARRIER COMPOSITIONS FOR DELIVERY OF THERAPEUTIC AGENTS, METHODS OF MAKING AND USING THE SAME | Pharmain, Ltd. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007076371-A2 | HYDROPHOBIC CORE CARRIER COMPOSITIONS FOR DELIVERY OF THERAPEUTIC AGENTS, METHODS OF MAKING AND USING THE SAME | PHARMAIN CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| US-20070141145-A1 | HYDROPHOBIC CORE CARRIER COMPOSITIONS FOR DELIVERY OF THERAPEUTIC AGENTS, METHODS OF MAKING AND USING THE SAME | PHARMALN LTD. (US) | 2007-06-21 | — | — | US | disclosed |