Propionic Acid

Propionic Acid

SCHEMBL45569

C=CCN.CCC(=O)O.CCC(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.56
ALDH1A1 P00352 4/20 0.50
TSHR P16473 5/20 0.43
GLRA1 P23415 1/20 0.40
SLC6A9 P48067 1/20 0.40
OR51E2 Q9H255 1/20 0.40
BLM P54132 4/20 0.36
GABRR1 P24046 4/20 0.36
GABRR2 P28476 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
LMNA P02545 3/20 0.36
GABRR3 A8MPY1 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
APEX1 P27695 1/20 0.36
ABCC4 O15439 1/20 0.36
MAPT P10636 1/20 0.36
HDAC3 O15379 2/20 0.35
HDAC1 Q13547 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC8 Q9BY41 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL386810 1.00
Propionic Acid SCHEMBL28776518 0.85
Allylamine SCHEMBL28448040 0.82 ALDH1A1 (0.56) FFAR3ALDH1A1TSHRGLRA1SLC6A9
Propionic Acid SCHEMBL31443224 0.82 FFAR3 (0.62) FFAR3ALDH1A1TSHRBLMTDP1
Glycine SCHEMBL4169207 0.82
Propionic Acid SCHEMBL31584345 0.82
Allylamine SCHEMBL461377 0.82
Butyric Acid SCHEMBL3813708 0.82 FFAR3 (0.62) FFAR3ALDH1A1TSHROR51E2BLM
Allylamine SCHEMBL28828732 0.82 ALDH1A1 (0.64) ALDH1A1TSHRGLRA1SLC6A9OR51E2
Allylamine SCHEMBL156788 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10307352-B2 Low oil compositions comprising a 4-substituted resorcinol and a high carbon chain ester JOHNSON & JOHNSON CONSUMER INC. (US) 2019-06-04 US claimed
US-20160367452-A1 LOW OIL COMPOSITIONS COMPRISING A 4-SUBSTITUTED RESORCINOL AND A HIGH CARBON CHAIN ESTER KENVUE BRANDS LLC 2016-12-22 US claimed
EP-2468246-B1 Skin cleansing compositions with polyglycerol esters and hydrophobically modified polymers JOHNSON & JOHNSON CONSUMER (US) 2014-01-22 EP claimed
US-8338348-B2 Skin cleansing compositions with polyglycerol esters and hydrophobically modified polymers JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2012-12-25 US claimed
EP-2468246-A1 Skin cleansing compositions with polyglycerol esters and hydrophobically modified polymers Johnson & Johnson Consumer Companies Inc. (US) 2012-06-27 EP claimed
US-20120157366-A1 SKIN CLEANSING COMPOSITIONS WITH POLYGLYCEROL ESTERS AND HYDROPHOBICALLY MODIFIED POLYMERS KENVUE BRANDS LLC 2012-06-21 US claimed
EP-1491594-B1 Black ink-jet inks HEWLETT PACKARD DEVELOPMENT CO (US) 2009-02-18 EP claimed
US-7387666-B2 Black ink-jet inks HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2008-06-17 US claimed
US-20040261658-A1 Black ink-jet inks HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2004-12-30 US claimed
EP-0117135-B1 DETERGENT COMPOSITIONS Johnson & Johnson Baby Products Company (US) 1990-07-25 EP claimed
US-4265782-A MODIFIED ROSIN ESTER AND A SURFACTANT JOHNSON & JOHNSON BABY PRODUCTS COMPANY (US) 1981-05-05 US claimed
WO-2024150173-A1 SKINCARE FORMULATIONS COMPRISING PHENYL PROPIONIC ACID DERIVATIVES AND METHODS USING SAME JOHNSON & JOHNSON CONSUMER INC. (US) 2024-07-18 WO disclosed
US-20240225975-A9 AN IMPROVED LONG WEARING SUNSCREEN COSMETIC BASF SE (DE) 2024-07-11 US disclosed
US-20240130940-A1 AN IMPROVED LONG WEARING SUNSCREEN COSMETIC BASF SE (DE) 2024-04-25 US disclosed
CN-117884252-A N-alkyl amino dicarboxylic salt collecting agent and application thereof 广州粤有研矿物资源科技有限公司 2024-04-16 CN disclosed
CN-1433458-A Stable, high glycerol liquids comprising N-acyl amino acids and/or salts UNILEVER NV (NL) 2003-07-30 CN disclosed
US-5139037-A Amphoteric polymer of betanized dialkylaminoalkyl (meth)acrylate or (meth)acrylamide and a cationic polymer L'OREAL (FR) 1992-08-18 US disclosed
US-5089252-A Amphoteric polymer of betainised dialkylaminoalkyl acrylate or dialkylaminoalkyl acrylamide and cationic deriative L'OREAL (FR) 1992-02-18 US disclosed
US-4710374-A TREATMENT OF HAIR, NAILS, SKIN L'OREAL (FR) 1987-12-01 US disclosed
US-4504644-A SUNSCREEN AGENTS L'OREAL (FR) 1985-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160367452-A1 LOW OIL COMPOSITIONS COMPRISING A 4-SUBSTITUTED RESORCINOL AND A HIGH CARBON CHAIN ESTER LRAT, CYP46A1, WDR48 FFAR3 93/4885ALDH1A1 1831/4885TSHR 4543/4885
US-10307352-B2 Low oil compositions comprising a 4-substituted resorcinol and a high carbon chain ester LRAT, CYP46A1, WDR48 FFAR3 93/4885ALDH1A1 1831/4885TSHR 4543/4885
US-20120157366-A1 SKIN CLEANSING COMPOSITIONS WITH POLYGLYCEROL ESTERS AND HYDROPHOBICALLY MODIFIED POLYMERS CUTA, DEGS1, PHOSPHO1 FFAR3 23/4885ALDH1A1 3403/4885TSHR 4798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.