SCHEMBL4557072

SCHEMBL4557072

C=Cc1ccc(C(=C)c2ccccc2C=O)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
LMNA P02545 2/20 0.39
MEN1 O00255 1/20 0.39
THRB P10828 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 5/20 0.38
TSHR P16473 2/20 0.38
TRIM24 O15164 1/20 0.37
TRIM33 Q9UPN9 1/20 0.37
TAS1R3 Q7RTX0 2/20 0.35
TAS1R1 Q7RTX1 2/20 0.35
PSMD14 O00487 1/20 0.32
ERN1 O75460 2/20 0.32
SRC P12931 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HDAC2 Q92769 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10978285 0.84 KMT2A (0.46) TDP1LMNAMEN1THRBBLM
SCHEMBL6520356 0.81 NR4A1 (0.42) TDP1LMNAMEN1THRBBLM
SCHEMBL27702698 0.78 ALDH1A1 (0.48) KMT2AALDH1A1TSHRTAS1R3TAS1R1
SCHEMBL7930451 0.74 ALDH1A1 (0.40) TDP1MEN1KMT2AALDH1A1TSHR
SCHEMBL8383017 0.74 ALDH1A1 (0.56) TDP1LMNAMEN1KMT2AALDH1A1
Ethane SCHEMBL27790628 0.72 MEN1 (0.40) LMNAMEN1KMT2AALDH1A1TSHR
SCHEMBL6525700 0.71 PARP1 (0.42) TDP1LMNAMEN1THRBBLM
Ethane SCHEMBL28057226 0.71 ALDH1A1 (0.52) TDP1LMNAMEN1KMT2AALDH1A1
SCHEMBL6520320 0.70 ALDH1A1 (0.55) TDP1LMNAMEN1THRBBLM
SCHEMBL1663839 0.70 CES2 (0.45) TDP1LMNAMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7531334-B2 Polymeric microcarriers for cell culture functions XEROX CORPORATION (US) 2009-05-12 US disclosed
US-20070243607-A1 POLYMERIC MICROCARRIERS FOR CELL CULTURE FUNCTIONS XEROX CORPORATION (US) 2007-10-18 US disclosed
US-7276254-B2 Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same XEROX CORPORATION (US) 2007-10-02 US disclosed
US-20030211035-A1 Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same XEROX CORPORATION 2003-11-13 US disclosed