Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 5/20 | 0.36 |
| ▸ | MMP1 | P03956 | 4/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 4/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967573 | 0.79 | PARP15 (0.60) | MMP2MMP9PARP15PARP14PARP10 | |
| SCHEMBL28279914 | 0.70 | PGR (0.54) | CA1CA2CA9MMP2ATM | |
| SCHEMBL919800 | 0.69 | F2 (0.48) | MMP13MMP1MMP2F2PPARG | |
| SCHEMBL918991 | 0.68 | MAPK14 (0.50) | CA1CA2CA9MMP13MMP1 | |
| SCHEMBL3967655 | 0.68 | FFAR1 (0.59) | MMP2MMP9PARP15PARP14PARP10 | |
| SCHEMBL2850028 | 0.68 | RIPK1 (0.49) | CA1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL3969644 | 0.68 | MAOB (0.57) | — | |
| SCHEMBL1067948 | 0.68 | MAOB (0.65) | PARP10PPARA | |
| SCHEMBL919807 | 0.67 | CYP2C19 (0.47) | ATMPPARAMEN1ALDH1A1KMT2A | |
| SCHEMBL919163 | 0.67 | SCN9A (0.47) | MMP13MMP1MMP2MMP9PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613296-B1 | METHODS FOR TREATMENT OF PARKINSON'S DISEASE | NEWRON PHARM SPA (IT) | 2009-07-01 | — | — | EP | disclosed |