SCHEMBL455719

SCHEMBL455719

CCCCOC(=O)C(CC)C(=O)OCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
ATM Q13315 1/20 0.47
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
TSHR P16473 4/20 0.44
HPGD P15428 1/20 0.44
TDP1 Q9NUW8 4/20 0.43
HCAR2 Q8TDS4 1/20 0.41
NAAA Q02083 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
ESR1 P03372 2/20 0.40
MAPT P10636 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
EPHX1 P07099 1/20 0.38
MAPK1 P28482 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2274671 0.94 ALDH1A1 (0.56) ALDH1A1ATMTSHRHPGDTDP1
SCHEMBL20836834 0.92 NAAA (0.52) ALDH1A1TSHRHCAR2NAAAESR1
SCHEMBL27436774 0.92 NAAA (0.52) ALDH1A1TSHRHCAR2NAAAESR1
SCHEMBL28049877 0.92 NAAA (0.52) ALDH1A1TSHRHCAR2NAAAESR1
SCHEMBL9472816 0.92 NAAA (0.52) ALDH1A1TSHRHCAR2NAAAESR1
SCHEMBL10557331 0.92 NAAA (0.52) ALDH1A1TSHRHCAR2NAAAESR1
SCHEMBL11540505 0.92 NAAA (0.52) ALDH1A1TSHRHCAR2NAAAESR1
SCHEMBL28518295 0.89 ALDH1A1 (0.52) ALDH1A1ATMTSHRHPGDTDP1
SCHEMBL452623 0.87 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ATSHRTDP1
SCHEMBL11874453 0.86 MEN1 (0.56) ALDH1A1ATMMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700654-A Copolyester for weather-resistant coating and preparation method and application thereof 中瀚新材料科技有限公司 2024-03-15 CN claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
JP-8269036-A None JP disclosed
US-20240191594-A1 Cement Top Jobs In Wellbore Annuli Using Expandable Compositions CHEVRON U.S.A. INC. 2024-06-13 US disclosed
CN-117700654-A Copolyester for weather-resistant coating and preparation method and application thereof 中瀚新材料科技有限公司 2024-03-15 CN disclosed
US-11884624-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2024-01-30 US disclosed
US-20240026206-A1 METHODS OF USING EXPANDABLE POLYMER GROUT FOR PLUG AND ABANDONMENT APPLICATIONS CHEVRON AUSTRALIA PTY LTD (AU) 2024-01-25 US disclosed
US-20240026749-A1 DEPLOYMENT METHODS FOR EXPANDABLE POLYMER GROUT FOR PLUG AND ABANDONMENT APPLICATIONS CHEVRON AUSTRALIA PTY LTD (AU) 2024-01-25 US disclosed
US-20230233500-A1 Gasdermin D (GSDMD) Succination for the Treatment of Inflammatory Disease UNIVERSITY OF MASSACHUSETTS 2023-07-27 US disclosed
CN-116474766-A Cerium oxide loaded manganese-zinc oxide catalyst, preparation method and method for preparing malonate derivative by using cerium oxide loaded manganese-zinc oxide catalyst 万华化学集团股份有限公司 2023-07-25 CN disclosed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP disclosed
US-5451458-A Electrography XEROX CORPORATION (US) 1995-09-19 US disclosed
US-5438110-A Homopolymerizing or copolymerizing olefins in presence of catalyst formed from solid component containing titanium, magnesium, halogen, electron donor, organoaluminum compound, organosilicon compound having cyclopentyl group MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-08-01 US disclosed
EP-0350170-B1 Process for polymerising olefins and polymerisation catalyst therefor MITSUI PETROCHEMICAL IND (JP) 1994-03-02 EP disclosed
US-4990479-A Coordination catalysts MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-02-05 US disclosed
EP-0385765-A2 Process for polymerizing olefins and catalyst for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-09-05 EP disclosed
EP-0350170-A2 Process for polymerising olefins and polymerisation catalyst therefor MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-01-10 EP disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11884624-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions PTGER4, PTGER1, PTGER3 ALDH1A1 654/4885ATM 3981/4885MEN1 3177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.