Acetic Acid

Acetic Acid

SCHEMBL4557323

C=CC[Sn+3].CC(=O)[O-].CC(=O)[O-].CC(=O)[O-]

nearest known ligand 0.47

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.47
ALDH1A1 P00352 3/20 0.40
CA4 P22748 2/20 0.35
BBOX1 O75936 2/20 0.34
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL2362050 0.97
Acrylic Acid SCHEMBL7154952 0.82 TSHR (0.37) ALDH1A1BBOX1TSHRLMNA
SCHEMBL10457405 0.82 BBOX1 (0.30) BBOX1TSHR
Fumaric Acid SCHEMBL1082736 0.80 CA1 (0.37) CA1ALDH1A1BBOX1LMNA
Fumaric Acid SCHEMBL1082740 0.80 CA1 (0.37) CA1ALDH1A1BBOX1LMNA
Thioglycolic Acid SCHEMBL1077110 0.78 BBOX1 (0.32) CA4BBOX1TSHR
Acetic Acid SCHEMBL1838684 0.77
Acetic Acid SCHEMBL28582335 0.74 CA1 (0.61) CA1ALDH1A1CA4TSHRLMNA
Acetic Acid SCHEMBL17164777 0.73 CA1 (0.73) CA1ALDH1A1CA4TSHRLMNA
Acetic Acid SCHEMBL135063 0.73 CA1 (0.89) CA1ALDH1A1CA4TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213703-A Mildew-proof composite elastomer 江苏绚中新材料科技有限公司 2022-03-22 CN claimed
US-10542755-B2 Agrochemical composition, method for its preparation and use thereof ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2020-01-28 US claimed
EP-2950646-B1 AGROCHEMICAL COMPOSITION, METHOD FOR ITS PREPARATION AND USE THEREOF ROTAM AGROCHEM INT CO LTD (CN) 2019-10-30 EP claimed
US-20150373979-A1 AGROCHEMICAL COMPOSITION, METHOD FOR ITS PREPARATION AND USE THEREOF ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) 2015-12-31 US claimed
EP-2950646-A1 AGROCHEMICAL COMPOSITION, METHOD FOR ITS PREPARATION AND USE THEREOF Rotam Agrochem International Co., Ltd (CN) 2015-12-09 EP claimed
WO-2014110942-A1 AGROCHEMICAL COMPOSITION, METHOD FOR ITS PREPARATION AND USE THEREOF ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) 2014-07-24 WO claimed
US-5910314-A DISPERSION IN AN AQUEOUS SOLUTION OF A SALT, AN EMULSIFIER, A POLYISOCYANATE AND A SALT WATER IMMISCIBLE MATERIAL TO FORM A POLYUREA SHELL WALL AMERICAN CYANAMID COMPANY (US) 1999-06-08 US claimed
EP-0148769-B1 PROCESS FOR PRODUCING MULTIPLE TYPES OF MICROCAPSULES STAUFFER CHEMICAL COMPANY (US) 1987-07-15 EP claimed
US-4643764-A Multiple types of microcapsules and their production STAUFFER CHEMICAL COMPANY (US) 1987-02-17 US claimed
EP-0148769-A1 Process for producing multiple types of microcapsules STAUFFER CHEMICAL COMPANY (US) 1985-07-17 EP claimed
US-4285720-A Encapsulation process and capsules produced thereby STAUFFER CHEMICAL COMPANY (US) 1981-08-25 US claimed
CN-114213703-A Mildew-proof composite elastomer 江苏绚中新材料科技有限公司 2022-03-22 CN disclosed
EP-2487192-B1 Microencapsulation of clomazone by means of a refined process and specific microcapsules produced thereof FMC CORP (US) 2021-03-03 EP disclosed
US-10542755-B2 Agrochemical composition, method for its preparation and use thereof ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2020-01-28 US disclosed
EP-2950646-B1 AGROCHEMICAL COMPOSITION, METHOD FOR ITS PREPARATION AND USE THEREOF ROTAM AGROCHEM INT CO LTD (CN) 2019-10-30 EP disclosed
EP-1840145-A1 Acetylene carbamide derivatives-polyurea polymers and microcapsules and formulations thereof for controlled release GAT Microencapsulation AG (AT) 2007-10-03 EP disclosed
EP-0148769-B1 PROCESS FOR PRODUCING MULTIPLE TYPES OF MICROCAPSULES STAUFFER CHEMICAL COMPANY (US) 1987-07-15 EP disclosed
US-4643764-A Multiple types of microcapsules and their production STAUFFER CHEMICAL COMPANY (US) 1987-02-17 US disclosed
EP-0148769-A1 Process for producing multiple types of microcapsules STAUFFER CHEMICAL COMPANY (US) 1985-07-17 EP disclosed
US-4285720-A Encapsulation process and capsules produced thereby STAUFFER CHEMICAL COMPANY (US) 1981-08-25 US disclosed