⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL437888 | 0.91 | ALDH1A1 (0.31) | — | |
| Phosphoric Acid SCHEMBL9574523 | 0.77 | FDPS (0.43) | — | |
| SCHEMBL14961843 | 0.77 | — | — | |
| SCHEMBL17662046 | 0.77 | — | — | |
| SCHEMBL10608081 | 0.76 | — | — | |
| SCHEMBL6831466 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL9801312 | 0.74 | — | — | |
| SCHEMBL28430474 | 0.74 | — | — | |
| SCHEMBL29039008 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL28648606 | 0.73 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101351518-B | Free radical-forming activator attached to solid and used to enhance CPM formulations | DUPONT AIR PROD NANOMATERIALS | 2012-03-21 | — | — | CN | disclosed |
| US-7531568-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2009-05-12 | — | — | US | disclosed |
| CN-101351518-A | Free radical-forming activator attached to solid and used to enhance CPM formulations | DUPONT AIR PROD NANOMATERIALS (US) | 2009-01-21 | — | — | CN | disclosed |
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
| US-20080234349-A1 | PPAR active compounds | PLEXXIKON INC. | 2008-09-25 | — | — | US | disclosed |
| EP-1943245-A2 | 1,3-DISUBSTITUTED INDOLE DERIVATIVES FOR USE AS PPAR MODULATORS | PLEXXIKON, INC. (US) | 2008-07-16 | — | — | EP | disclosed |
| US-20080119483-A1 | COMPOSITIONS AND METHODS FOR INHIBITING PROTOZOAN GROWTH | WASHINGTON UNIVERSITY IN ST. LOUIS (US) | 2008-05-22 | — | — | US | disclosed |
| EP-1833787-A2 | INDOLE DERIVATIVES FOR USE AS PPAR ACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2007-09-19 | — | — | EP | disclosed |
| EP-1819673-A2 | INDOLE DERIVATIVES FOR USE AS PPAR ACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2007-08-22 | — | — | EP | disclosed |
| US-20070072904-A1 | 1-arylsulfone-substituted indole carboxylic acids or amides; peroxisome proliferator-activated receptor PPAR modulators; obesity, diabetes, cardiovascular disorders | PLEXXIKON INC | 2007-03-29 | — | — | US | disclosed |
| WO-2007030559-A2 | 1, 3-DISUBSTITUTED INDOLE DERIVATIVES FOR USE AS PPAR MODULATORS | PLEXXIKON, INC. (US) | 2007-03-15 | — | — | WO | disclosed |
| US-20060135540-A1 | PPAR active compounds | PLEXXIKON, INC. | 2006-06-22 | — | — | US | disclosed |
| WO-2006060535-A2 | INDOLE DERIVATIVES FOR USE AS PPAR ACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
| WO-2006060456-A2 | INDOLE DERIVATIVES FOR USE AS PPAR PPAR ACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
| US-20060116416-A1 | PPAR active compounds | PLEXXIKON, INC | 2006-06-01 | — | — | US | disclosed |