Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19909887 | 0.87 | KDM1A (0.44) | KDM1ARCOR1L3MBTL1CA1IDO1 | |
| SCHEMBL433347 | 0.84 | KDM1A (0.41) | KDM1ARCOR1L3MBTL1CA1IDO1 | |
| SCHEMBL430807 | 0.84 | KDM1A (0.41) | KDM1ARCOR1L3MBTL1CA1IDO1 | |
| SCHEMBL20703377 | 0.75 | KDM1A (0.39) | KDM1ARCOR1L3MBTL1CA1IDO1 | |
| SCHEMBL17724399 | 0.74 | KDM1A (0.44) | KDM1ARCOR1L3MBTL1CA1IDO1 | |
| SCHEMBL456182 | 0.73 | KDM1A (0.40) | KDM1ARCOR1L3MBTL1CA1CHRNA1 | |
| SCHEMBL448908 | 0.71 | KDM1A (0.41) | KDM1ARCOR1L3MBTL1CA1IDO1 | |
| SCHEMBL430645 | 0.71 | KDM1A (0.41) | KDM1ARCOR1L3MBTL1CA1IDO1 | |
| SCHEMBL450566 | 0.71 | KDM1A (0.41) | KDM1ARCOR1L3MBTL1CA1IDO1 | |
| SCHEMBL21523837 | 0.71 | CHRNB2 (0.48) | KDM1ARCOR1CA1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012034095-A1 | COMPOUNDS AND COMPOSITIONS AS TRK INHIBITORS | IRM LLC (BM) | 2012-03-15 | — | — | WO | disclosed |