⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18545242 | 1.00 | MAP3K14 (0.33) | — | |
| SCHEMBL3628793 | 1.00 | MAP3K14 (0.33) | — | |
| SCHEMBL5909395 | 0.84 | ALDH1A1 (0.31) | — | |
| SCHEMBL2548921 | 0.82 | CRBN (0.36) | — | |
| SCHEMBL6016837 | 0.82 | MEN1 (0.30) | — | |
| SCHEMBL2548118 | 0.82 | CRBN (0.36) | — | |
| SCHEMBL3842201 | 0.82 | — | — | |
| SCHEMBL10615877 | 0.82 | KDM4E (0.33) | — | |
| SCHEMBL21880340 | 0.82 | CRBN (0.42) | — | |
| SCHEMBL16364840 | 0.80 | ACHE (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452984-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | Molecure S.A. (PL) | 2024-10-30 | — | — | EP | claimed |
| US-20230219973-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-07-13 | — | — | US | claimed |
| WO-2023119233-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-06-29 | — | — | WO | claimed |
| US-7112586-B2 | Substituted diamine derivatives useful as motilin antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2006-09-26 | — | — | US | claimed |
| US-20050148584-A1 | Novel substituted diamine derivatives useful as motilin antagonists | JOHNSON SIGMOND G (US) | 2005-07-07 | — | — | US | claimed |
| US-20030203906-A1 | A phenylamide derivatives for treating gastrointestinal reflux disorders, eating disorder obesity and irritable bowel disorder | JOHNSON SIGMONG G (US) | 2003-10-30 | — | — | US | claimed |
| EP-1294695-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-03-26 | — | — | EP | claimed |
| US-20020013352-A1 | For therapy of gastrointestinal reflux disorders, eating disorders leading to obesity and irritable bowel disorder | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-01-31 | — | — | US | claimed |
| WO-2001085694-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-15 | — | — | WO | claimed |
| EP-0011321-A1 | Pyrrolidine derivatives and process for the preparation of such compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-05-28 | — | — | EP | claimed |
| JP-10067741-A | — | — | None | — | — | JP | disclosed |
| EP-4688740-A1 | FUSED PYRROLIDINE-2-ONE HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2026-02-11 | — | — | EP | disclosed |
| EP-4230264-B1 | PRODRUGS OF FUMARATES AND THEIR USE IN TREATING VARIOUS DESEASES | ALKERMES PHARMA IRELAND LTD (IE) | 2026-01-28 | — | — | EP | disclosed |
| US-12404279-B2 | Deubiquitinase inhibitors and methods of use thereof | MOLECURE S.A. (PL) | 2025-09-02 | — | — | US | disclosed |
| WO-2025106362-A1 | RIPK1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2025-05-22 | — | — | WO | disclosed |
| EP-0818446-A1 | Process for preparing 2,4-dioxo-3-azabicyclo(3.1.0)hexanes | Pfizer Limited (GB) | 1998-01-14 | — | — | EP | disclosed |
| EP-0685995-A1 | ENHANCER COMPOSITION FOR AGRICULTURAL CHEMICALS AND AGRICULTURAL CHEMICAL COMPOSITION | Kao Corporation (JP) | 1995-12-13 | — | — | EP | disclosed |
| WO-1995017817-A1 | ENHANCER COMPOSITION FOR AGRICULTURAL CHEMICALS AND AGRICULTURAL CHEMICAL COMPOSITION | KAO CORPORATION (JP) | 1995-07-06 | — | — | WO | disclosed |
| EP-0011321-A1 | Pyrrolidine derivatives and process for the preparation of such compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-05-28 | — | — | EP | disclosed |
| EP-0011321-A1 | Pyrrolidine derivatives and process for the preparation of such compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-05-28 | — | — | EP | disclosed |