Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | SPR | P35270 | 3/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812986 | 0.89 | MAPK1 (0.34) | DRD1PARP1SPRGRM5 | |
| SCHEMBL3813694 | 0.89 | KMT2A (0.35) | DRD1PARP1SPRGRM5 | |
| SCHEMBL3821854 | 0.89 | GRM5 (0.31) | GRM5 | |
| SCHEMBL3820726 | 0.89 | HTT (0.35) | SPRGRM5 | |
| SCHEMBL4559837 | 0.86 | DRD1 (0.34) | DRD1SPR | |
| SCHEMBL3811690 | 0.85 | MAPK1 (0.35) | PARP1SPRGRM5 | |
| SCHEMBL3810604 | 0.84 | KMT2A (0.36) | PARP1SPR | |
| SCHEMBL4181173 | 0.82 | BRD4 (0.33) | — | |
| SCHEMBL3813237 | 0.81 | GRM5 (0.33) | PARP1SPRGRM5 | |
| SCHEMBL3810606 | 0.81 | PARP1 (0.36) | DRD1PARP1SPRGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |