Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444725 | 0.84 | GPR119 (1.00) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL114213 | 0.84 | GPR119 (1.00) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL514572 | 0.81 | GPR119 (0.66) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL2734562 | 0.79 | GPR119 (0.89) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL388948 | 0.78 | GPR119 (1.00) | GPR119 | |
| SCHEMBL15690371 | 0.78 | GPR119 (0.64) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL1673975 | 0.77 | GPR119 (1.00) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL27852838 | 0.77 | GPR119 (0.62) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL1673694 | 0.76 | GPR119 (0.81) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL4980143 | 0.76 | GPR119 (0.62) | GPR119CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1808168-B1 | Combination therapy for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood GLP-1 level | ARENA PHARM INC (US) | 2009-06-03 | — | — | EP | disclosed |