Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | LGMN | Q99538 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.31 |
| ▸ | F12 | P00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987180 | 0.79 | PTPN11 (0.42) | PKMPTPN11LGMNTACR2HRH4 | |
| SCHEMBL183766 | 0.71 | CRHR1 (0.37) | — | |
| SCHEMBL2268526 | 0.71 | MAPT (0.38) | — | |
| SCHEMBL4557846 | 0.69 | KMT2A (0.60) | PTPN11 | |
| SCHEMBL7617215 | 0.68 | HRH1 (0.46) | HRH4 | |
| Formaldehyde SCHEMBL8047178 | 0.68 | CRHR1 (0.36) | — | |
| SCHEMBL11591477 | 0.64 | CRHR1 (0.49) | — | |
| SCHEMBL29152865 | 0.64 | PDE4A (0.35) | — | |
| SCHEMBL8057734 | 0.64 | HSD17B10 (0.41) | — | |
| SCHEMBL4557553 | 0.64 | TACR2 (0.40) | PTPN11LGMNTACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |