Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SORD | Q00796 | 1/20 | 0.35 |
| ▸ | LGMN | Q99538 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9086580 | 0.82 | TACR2 (0.44) | TACR2POLBMAPTL3MBTL1PTPN11 | |
| SCHEMBL9083987 | 0.79 | MAPT (0.43) | POLBMAPTL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL6987180 | 0.78 | PTPN11 (0.42) | TACR2MAPTPTPN11ALDH1A1SMN1; SMN2 | |
| SCHEMBL9083863 | 0.77 | MAPT (0.44) | TACR2MAPTPTPN11HSD17B10ALDH1A1 | |
| SCHEMBL9948445 | 0.75 | KMT2A (0.50) | MAPTL3MBTL1HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL12490953 | 0.75 | PTPN11 (0.43) | TACR2POLBMAPTPTPN11HSD17B10 | |
| SCHEMBL6351916 | 0.75 | MAPT (0.45) | POLBMAPTHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9418612 | 0.75 | SORD (0.49) | MAPTL3MBTL1HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL38827 | 0.74 | MAPT (0.57) | POLBMAPTL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL10609657 | 0.72 | CYP3A4 (0.51) | POLBMAPTPTPN11HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |