Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469344 | 1.00 | EP300 (0.50) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL12276568 | 0.92 | ALDH1A1 (0.40) | EP300TERTCYP1A2MAPTCYP2C19 | |
| SCHEMBL8850177 | 0.85 | EP300 (0.60) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL8849620 | 0.85 | EP300 (0.60) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL5083255 | 0.85 | EP300 (0.60) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL15281927 | 0.83 | EP300 (0.48) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL5083310 | 0.82 | EP300 (0.57) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL27908572 | 0.80 | EP300 (0.46) | EP300CYP1A2MAPTCYP2C19BLM | |
| SCHEMBL27908566 | 0.79 | FAAH (0.51) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL27908560 | 0.79 | EP300 (0.44) | EP300TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1714977-B1 | Synthesis of cyclosporin analogs | ISOTECHNIKA INC (CA) | 2009-03-11 | — | — | EP | claimed |