Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.63 |
| ▸ | NR3C2 | P08235 | 16/20 | 0.63 |
| ▸ | PGR | P06401 | 14/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292319 | 0.96 | NR3C1 (0.69) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4555748 | 0.93 | NR3C1 (0.65) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL292734 | 0.92 | NR3C1 (0.67) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL293515 | 0.88 | NR3C1 (0.73) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL292292 | 0.88 | NR3C1 (0.72) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL292075 | 0.87 | NR3C1 (0.71) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL292257 | 0.86 | NR3C1 (0.70) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL291658 | 0.86 | NR3C1 (0.70) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL14158607 | 0.86 | NR3C1 (0.65) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL292412 | 0.83 | NR3C1 (0.81) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051736-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST AND AN IMMUNOSUPPRESSIVE AGENT FOR TREATING DRY EYE | Bausch & Lomb Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008005686-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST AND AN IMMUNOSUPPRESSIVE AGENT FOR TREATING DRY EYE | BAUSCH & LOMB INCORPORATED (US) | 2008-01-10 | — | — | WO | disclosed |