Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | METAP2 | P50579 | 1/20 | 0.58 |
| ▸ | METAP1 | P53582 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460486 | 0.74 | LMNA (0.64) | LMNAMETAP2METAP1HDAC6KMT2A | |
| Benzoxiquine SCHEMBL29729484 | 0.74 | LMNA (1.00) | LMNAMETAP2METAP1HDAC6KMT2A | |
| Benzoxiquine SCHEMBL360626 | 0.74 | LMNA (1.00) | LMNAMETAP2METAP1HDAC6KMT2A | |
| Benzoxiquine SCHEMBL30599448 | 0.74 | LMNA (1.00) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL14248985 | 0.73 | KMT2A (0.63) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL23124841 | 0.72 | KMT2A (0.58) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL12355077 | 0.72 | KMT2A (0.61) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL10036520 | 0.71 | KMT2A (0.67) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL725404 | 0.71 | KMT2A (0.76) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL30874080 | 0.71 | KMT2A (0.70) | LMNAMETAP2METAP1HDAC6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |