Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | METAP2 | P50579 | 1/20 | 0.64 |
| ▸ | METAP1 | P53582 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358679 | 0.86 | PARP1 (0.56) | LMNAMETAP2METAP1HDAC6PARP1 | |
| SCHEMBL7466188 | 0.83 | PARP1 (0.56) | LMNAMETAP2METAP1HDAC6PARP1 | |
| Benzoxiquine SCHEMBL30599448 | 0.79 | LMNA (1.00) | LMNAMETAP2METAP1HDAC6KDM4E | |
| Benzoxiquine SCHEMBL360626 | 0.79 | LMNA (1.00) | LMNAMETAP2METAP1HDAC6KDM4E | |
| Benzoxiquine SCHEMBL29729484 | 0.79 | LMNA (1.00) | LMNAMETAP2METAP1HDAC6KDM4E | |
| SCHEMBL27574877 | 0.78 | LMNA (0.53) | LMNAMETAP2METAP1HDAC6KDM4E | |
| SCHEMBL15868230 | 0.76 | LMNA (0.72) | LMNAMETAP2METAP1HDAC6KDM4E | |
| SCHEMBL434888 | 0.75 | HPGDS (0.62) | LMNAPARP1KDM4EMAPTPSMD14 | |
| SCHEMBL4558091 | 0.74 | LMNA (0.58) | LMNAMETAP2METAP1HDAC6PARP1 | |
| Benzoxiquine SCHEMBL10868407 | 0.74 | LMNA (0.89) | LMNAMETAP2METAP1HDAC6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747362-B1 | Substituted quinoline herbicide intermediates and process | BASF AG (DE) | 2002-10-30 | — | — | EP | disclosed |
| EP-0812828-B1 | Process for the preparation of (5,6-dicarboxy-3-pyridyl) methyl ammonium halides | BASF AG (DE) | 2002-03-13 | — | — | EP | disclosed |
| US-6002012-A | Process for the preparation of [(5,6-dicarboxy-3-pyridyl) methyl] ammonium halides | AMERICAN CYANAMID COMPANY (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0812828-A1 | Process for the preparation of (5,6-dicarboxy-3-pyridyl) methyl ammonium halides | American Cyanamid Company (US) | 1997-12-17 | — | — | EP | disclosed |
| EP-0747362-A1 | Substituted quinoline herbicide intermediates and process | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | disclosed |