Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.64 |
| ▸ | FYN | P06241 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.64 |
| ▸ | GRB2 | P62993 | 1/20 | 0.64 |
| ▸ | HSD17B3 | P37058 | 12/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868543 | 0.99 | LCK (0.65) | LCKFYNAKR1B1GRB2HSD17B3 | |
| SCHEMBL2791708 | 0.84 | AKR1B1 (0.74) | LCKFYNAKR1B1GRB2HSD17B3 | |
| SCHEMBL16197641 | 0.83 | HSD17B3 (0.64) | LCKFYNAKR1B1GRB2HSD17B3 | |
| SCHEMBL10093731 | 0.82 | ALDH1A1 (0.71) | LCKFYNAKR1B1GRB2HSD17B3 | |
| SCHEMBL14618025 | 0.81 | ALDH1A1 (0.69) | LCKFYNAKR1B1GRB2HSD17B3 | |
| SCHEMBL23326972 | 0.79 | LCK (0.73) | LCKFYNAKR1B1GRB2HSD17B3 | |
| SCHEMBL263980 | 0.78 | AKR1B1 (1.00) | LCKFYNAKR1B1GRB2HSD17B3 | |
| SCHEMBL4215955 | 0.77 | HSD17B3 (0.75) | LCKFYNAKR1B1GRB2HSD17B3 | |
| SCHEMBL8396287 | 0.76 | HSD17B3 (0.69) | LCKFYNAKR1B1GRB2HSD17B3 | |
| SCHEMBL536846 | 0.76 | HSD17B3 (1.00) | LCKFYNAKR1B1GRB2HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018429-A1 | GENETICALLY ENCODED FLUORESCENT COUMARIN AMINO ACIDS | The Scrips Research Institute (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007139870-A1 | GENETICALLY ENCODED FLUORESCENT COUMARIN AMINO ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-12-06 | — | — | WO | disclosed |