Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1290429 | 0.85 | CHRNB2 (0.41) | CHRNB2CHRNA4SIGMAR1CHRNA7 | |
| SCHEMBL2203 | 0.71 | NPC1 (0.42) | — | |
| SCHEMBL2432002 | 0.71 | — | — | |
| SCHEMBL3937255 | 0.71 | CHRNB2 (0.38) | CHRNB2CHRNA4SIGMAR1CHRNA7 | |
| Hydrochloric Acid SCHEMBL16600475 | 0.69 | CHRNB2 (0.55) | CHRNB2CHRNA4SIGMAR1CHRNA7 | |
| Hydrochloric Acid SCHEMBL18230043 | 0.69 | CHRNB2 (0.55) | CHRNB2CHRNA4SIGMAR1CHRNA7 | |
| Bromide SCHEMBL8686784 | 0.69 | CHRNB2 (0.55) | CHRNB2CHRNA4SIGMAR1CHRNA7 | |
| Bromide SCHEMBL8691876 | 0.69 | CHRNB2 (0.55) | CHRNB2CHRNA4SIGMAR1CHRNA7 | |
| SCHEMBL449234 | 0.69 | CHRNB2 (0.37) | CHRNB2CHRNA4SIGMAR1CHRNA7 | |
| SCHEMBL3414893 | 0.68 | SIGMAR1 (0.54) | CHRNB2CHRNA4SIGMAR1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128918-A1 | COMBINATION THERAPY USING A SOLUBLE HYALURONIDASE AND A BISPHOSPHONATE | HALOZYME, INC. (US) | 2009-10-22 | — | — | WO | disclosed |