SCHEMBL4558397

SCHEMBL4558397

c1ccc2c(c1)ccn1cc(-c3ccc(-c4ccc5ccc6cccc7ccc4c5c67)cc3)nc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.58
RAB9A P51151 8/20 0.58
NPC1 O15118 7/20 0.58
KDM4E B2RXH2 5/20 0.58
MAPT P10636 3/20 0.58
TP53 P04637 3/20 0.58
NFKB1 P19838 3/20 0.58
NFKB2 Q00653 3/20 0.58
RELA Q04206 3/20 0.58
HPGD P15428 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
LMNA P02545 1/20 0.58
BLM P54132 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ALDH1A3 P47895 6/20 0.45
ALDH1A2 O94788 3/20 0.45
HSD17B10 Q99714 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11886013 0.82 ALDH1A1 (0.53) ALDH1A1RAB9ANPC1KDM4EMAPT
SCHEMBL11886019 0.82 ALDH1A1 (0.52) ALDH1A1RAB9ANPC1KDM4EMAPT
SCHEMBL11252935 0.80 ALDH1A1 (0.72) ALDH1A1RAB9ANPC1KDM4EMAPT
SCHEMBL4557225 0.80 RAB9A (0.56) ALDH1A1RAB9ANPC1KDM4EMAPT
SCHEMBL11419932 0.79 ALDH1A1 (0.71) ALDH1A1RAB9ANPC1KDM4EMAPT
SCHEMBL13821031 0.78 ALDH1A1 (0.43) ALDH1A1RAB9ANPC1KDM4EMAPT
SCHEMBL11886026 0.78 ALDH1A1 (0.50) ALDH1A1RAB9ANPC1KDM4EMAPT
SCHEMBL13325832 0.77 ALDH1A1 (0.68) ALDH1A1RAB9ANPC1KDM4EMAPT
SCHEMBL14767823 0.77 RAB9A (0.68) ALDH1A1RAB9ANPC1KDM4EMAPT
SCHEMBL13325835 0.77 ALDH1A1 (0.72) ALDH1A1RAB9ANPC1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2157627-B1 Organic light emitting diode including light-efficiency-improvement layer SAMSUNG DISPLAY CO LTD (KR) 2013-01-23 EP disclosed
US-8343638-B2 Organic light emitting diode including light-efficiency-improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2013-01-01 US disclosed
US-8343638-B2 Organic light emitting diode including light-efficiency-improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2013-01-01 US disclosed
EP-2157627-A1 Organic light emitting diode including light-efficiency-improvement layer Samsung Mobile Display Co., Ltd. (KR) 2010-02-24 EP disclosed
US-20100039029-A1 Organic Light Emitting Diode Including Light-Efficiency-Improvement Layer SAMSUNG DISPLAY CO., LTD. (KR) 2010-02-18 US disclosed
US-20100039029-A1 Organic Light Emitting Diode Including Light-Efficiency-Improvement Layer SAMSUNG DISPLAY CO., LTD. (KR) 2010-02-18 US disclosed
US-20090153035-A1 Heteroaromatic cycle-containing compound, method of preparing the same and organic light emitting device comprising the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2009-06-18 US disclosed
US-20090153035-A1 Heteroaromatic cycle-containing compound, method of preparing the same and organic light emitting device comprising the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2009-06-18 US disclosed
US-20090153035-A1 Heteroaromatic cycle-containing compound, method of preparing the same and organic light emitting device comprising the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090153035-A1 Heteroaromatic cycle-containing compound, method of preparing the same and organic light emitting device comprising the same CCNE2, CCNC, CCNT1 ALDH1A1 337/4885RAB9A 3359/4885NPC1 2205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.