Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547309 | 0.84 | CA1 (0.42) | MEN1KMT2AF2PRSS1ITGB3 | |
| SCHEMBL6775524 | 0.83 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MAPTHSD17B10 | |
| SCHEMBL202931 | 0.82 | ITGB3 (0.51) | F2PLGPLAUPLATKLKB1 | |
| SCHEMBL8758371 | 0.79 | KDM4E (0.42) | SMN1; SMN2KDM4EGPR35MEN1KMT2A | |
| SCHEMBL8758378 | 0.79 | KDM4E (0.42) | SMN1; SMN2KDM4EGPR35MEN1KMT2A | |
| SCHEMBL27999432 | 0.78 | PARP1 (0.50) | MEN1KMT2A | |
| SCHEMBL11441110 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9706327 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL14535305 | 0.77 | MEN1 (0.50) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL17785165 | 0.76 | KMT2A (0.58) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511721-B1 | GUANIDINO PHENYLALANIN COMPOUNDS USED AS UROKINASE INHIBITORS | WILEX AG (DE) | 2009-07-01 | — | — | EP | disclosed |
| EP-1511721-A2 | GUANIDINO PHENYLALANIN COMPOUNDS USED AS UROKINASE INHIBITORS | Wilex AG (DE) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003103644-A3 | GUANIDINO PHENYLALANIN COMPOUNDS USED AS UROKINASE INHIBITORS | WILEX AG (DE) | 2004-04-01 | — | — | WO | disclosed |
| WO-2003103644-A2 | GUANIDINO PHENYLALANIN COMPOUNDS USED AS UROKINASE INHIBITORS | WILEX AG (DE) | 2003-12-18 | — | — | WO | disclosed |