SCHEMBL4558608

SCHEMBL4558608

O=C(O)CCCCCCCCCCCCCC1=CCCC1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
F13A1 P00488 3/20 0.47
MAPT P10636 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
LMNA P02545 2/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44
PMP22 Q01453 1/20 0.44
SCD O00767 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HPGD P15428 2/20 0.42
TAAR1 Q96RJ0 1/20 0.42
TBXAS1 P24557 1/20 0.40
FFAR4 Q5NUL3 1/20 0.39
EPHX1 P07099 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2477399 1.00 F13A1 (0.47) F13A1MAPTRXFP1LMNATSHR
SCHEMBL27641655 1.00 F13A1 (0.47) F13A1MAPTRXFP1LMNATSHR
SCHEMBL31261412 1.00 F13A1 (0.47) F13A1MAPTRXFP1LMNATSHR
SCHEMBL9533116 1.00 F13A1 (0.47) F13A1MAPTRXFP1LMNATSHR
SCHEMBL28343241 0.98 ALDH1A1 (0.44) F13A1MAPTRXFP1LMNATSHR
SCHEMBL11801847 0.95 ALDH1A1 (0.49) F13A1MAPTRXFP1LMNATSHR
SCHEMBL7150330 0.95 ALDH1A1 (0.49) F13A1MAPTRXFP1LMNATSHR
SCHEMBL988106 0.93 ALDH1A1 (0.50) MAPTLMNANFKB1ALDH1A1MEN1
SCHEMBL12132006 0.92 ALDH1A1 (0.49) MAPTLMNANFKB1ALDH1A1MEN1
SCHEMBL987088 0.87 ALDH1A1 (0.55) MAPTLMNANFKB1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090209485-A1 MODULATING ANGIOGENESIS WITH NOD FACTORS SUCH AS GLUCOSAMINE OLIGOSACCHARIDES PARISH CHRISTOPHER RICHARD 2009-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209485-A1 MODULATING ANGIOGENESIS WITH NOD FACTORS SUCH AS GLUCOSAMINE OLIGOSACCHARIDES FLT4, UGGT1, FLT1 F13A1 842/4885MAPT 4721/4885RXFP1 199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.