Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 17/20 | 0.42 |
| ▸ | MAOA | P21397 | 15/20 | 0.42 |
| ▸ | MAOB | P27338 | 15/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.37 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560516 | 0.85 | KCNQ3 (0.38) | KDM1AMAOAMAOBALOX5KCNQ3 | |
| SCHEMBL4558507 | 0.82 | KCNQ3 (0.40) | KDM1AEPHX1KCNQ3KCNQ2KCNQ4 | |
| SCHEMBL28046467 | 0.81 | ALOX5 (0.40) | ALOX5EPHX1 | |
| SCHEMBL21438985 | 0.76 | KDM1A (0.44) | KDM1AMAOAMAOB | |
| SCHEMBL4862021 | 0.72 | KMT2A (0.39) | EPHX1KCNQ3KCNQ2 | |
| SCHEMBL15542258 | 0.70 | KDM1A (0.55) | KDM1AMAOAMAOB | |
| SCHEMBL15541944 | 0.70 | KDM1A (0.55) | KDM1AMAOAMAOB | |
| SCHEMBL27932361 | 0.70 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL28318116 | 0.70 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL6623618 | 0.70 | KDM1A (0.55) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC11, HDAC3 | KDM1A 29/4885MAOA 207/4885MAOB 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.