Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558684 | 0.81 | KDM1A (0.42) | ALOX5EPHX1 | |
| SCHEMBL4560516 | 0.76 | KCNQ3 (0.38) | ALOX5LMNAHPGDTRPM8KMT2A | |
| SCHEMBL4862021 | 0.75 | KMT2A (0.39) | EPHX1LMNAHPGDKMT2ARECQL | |
| SCHEMBL4558507 | 0.73 | KCNQ3 (0.40) | EPHX1LMNAHPGDKMT2ARECQL | |
| SCHEMBL27306852 | 0.73 | EPHX1 (0.33) | EPHX1ALDH1A1 | |
| SCHEMBL27932361 | 0.73 | ALOX5 (0.44) | ALOX5LMNAHPGDKMT2ACYP2D6 | |
| SCHEMBL28318116 | 0.73 | ALOX5 (0.44) | ALOX5LMNAHPGDKMT2ACYP2D6 | |
| SCHEMBL3387663 | 0.70 | ALOX5 (0.42) | ALOX5EPHX1LMNAHPGDEPHX2 | |
| SCHEMBL517632 | 0.69 | ALOX5 (0.41) | ALOX5EPHX1LMNAHPGDKMT2A | |
| SCHEMBL4973208 | 0.68 | MEN1 (0.39) | ALOX5EPHX1LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261167-B | 6 of replacement, 6-condenses nitrogen-containing heterocycle compound and uses thereof | HOFFMAN-LA ROCHE LTD. (CH) | 2016-05-04 | — | — | CN | disclosed |