Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.73 |
| ▸ | FOS | P01100 | 1/20 | 0.66 |
| ▸ | TTR | P02766 | 1/20 | 0.66 |
| ▸ | JUN | P05412 | 1/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.66 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.66 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.66 |
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terameprocol SCHEMBL10060164 | 0.96 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN | |
| Terameprocol SCHEMBL2356280 | 0.96 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN | |
| Terameprocol SCHEMBL30094578 | 0.96 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN | |
| Terameprocol SCHEMBL29794162 | 0.96 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN | |
| Terameprocol SCHEMBL194588 | 0.96 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL14238533 | 0.87 | ALOX15 (0.67) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL15160938 | 0.87 | ALOX15 (0.67) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL14864105 | 0.87 | ALOX15 (0.67) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL16323169 | 0.87 | ALOX15 (0.71) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL10026174 | 0.86 | ALOX15 (0.65) | ALOX15ALOX12FOSTTRJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111205171-A | New synthetic method of nordihydroguaiaretic acid (NDGA) | 晋城天成科创股份有限公司 | 2020-05-29 | — | — | CN | claimed |
| WO-1988001509-A1 | PHARMACOLOGICALLY ACTIVE COMPOSITIONS OF CATECHOLIC BUTANES WITH ZINC | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-03-10 | — | — | WO | claimed |
| CN-111205171-A | New synthetic method of nordihydroguaiaretic acid (NDGA) | 晋城天成科创股份有限公司 | 2020-05-29 | — | — | CN | disclosed |
| CN-111205171-A | New synthetic method of nordihydroguaiaretic acid (NDGA) | 晋城天成科创股份有限公司 | 2020-05-29 | — | — | CN | disclosed |
| CN-103585136-A | Methods and compositions for delivery of catecholic butanes for treatment of tumors | UNIV JOHNS HOPKINS | 2014-02-19 | — | — | CN | disclosed |
| EP-2637649-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | Akron Molecules GmbH (AT) | 2013-09-18 | — | — | EP | disclosed |
| CN-101150955-B | Oral formulations for delivery of catecholic butanes including NDGA compounds | ERIMOS PHARMACEUTICALS LLC | 2013-04-17 | — | — | CN | disclosed |
| WO-2012062925-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | AKRON MOLECULES GMBH (AT) | 2012-05-18 | — | — | WO | disclosed |
| CN-1852705-A | Methods and compositions for delivery of catecholic butanes for treatment of obesity | ERIMOS PHARMACEUTICAL LLP (US) | 2006-10-25 | — | — | CN | disclosed |
| CN-1849115-A | Methods and compositions for delivery of catecholic butanes for treatment of tumors | UNIV JOHNS HOPKINS (US) | 2006-10-18 | — | — | CN | disclosed |
| CN-1838948-A | Methods and compositions for delivery of catecholic butanes for treatment of diseases | ERIMOS PHARMACEUTICAL LLP (US) | 2006-09-27 | — | — | CN | disclosed |
| EP-0297733-A2 | Pharmaceutical compositions comprising catecholic butanes | BLOCK DRUG COMPANY, INC. (US) | 1989-01-04 | — | — | EP | disclosed |