Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7133299 | 0.81 | — | — | |
| SCHEMBL4561971 | 0.70 | CYP3A4 (0.39) | PDE4APDE4BPDE4CPDE4DCA2 | |
| SCHEMBL1201869 | 0.64 | CYP3A4 (0.46) | PDE4APDE4BPDE4CPDE4DCA2 | |
| SCHEMBL29422790 | 0.64 | CYP3A4 (0.46) | PDE4APDE4BPDE4CPDE4DCA2 | |
| SCHEMBL4571012 | 0.64 | CYP3A4 (0.46) | PDE4APDE4BPDE4CPDE4DCA2 | |
| SCHEMBL7519367 | 0.62 | — | — | |
| SCHEMBL19014916 | 0.60 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4DCA2 | |
| SCHEMBL1276533 | 0.59 | CYP3A4 (0.59) | PDE4APDE4BPDE4CPDE4DCA2 | |
| SCHEMBL25143222 | 0.59 | MTNR1A (0.45) | PDE4APDE4BPDE4CPDE4DALOX15 | |
| SCHEMBL28383858 | 0.58 | SNCA (0.53) | PDE4APDE4BPDE4CPDE4DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062975-A1 | NOVEL TRIARYLMETHYL RADICALS: PREPARATION AND USE THEREOF | PHOSPHOENIX SARL (FR) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062975-A1 | NOVEL TRIARYLMETHYL RADICALS: PREPARATION AND USE THEREOF | PHOSPHOENIX SARL (FR) | 2012-05-18 | — | — | WO | disclosed |