Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29422790 | 1.00 | CYP3A4 (0.46) | CYP3A4MAPTALDH1A1KDM4ECA2 | |
| SCHEMBL1201869 | 1.00 | CYP3A4 (0.46) | CYP3A4MAPTALDH1A1KDM4ECA2 | |
| SCHEMBL9511322 | 0.82 | GAA (0.50) | MAPTALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL9507682 | 0.82 | GRIN2D (0.44) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3051919 | 0.80 | CYP3A4 (0.36) | CYP3A4MAPTALDH1A1KDM4ECA2 | |
| SCHEMBL28383858 | 0.80 | SNCA (0.53) | CYP3A4MAPTALDH1A1KDM4EACHE | |
| SCHEMBL38661182 | 0.80 | CYP3A4 (0.36) | CYP3A4MAPTALDH1A1KDM4ECA2 | |
| SCHEMBL1276533 | 0.75 | CYP3A4 (0.59) | CYP3A4MAPTALDH1A1KDM4ECA2 | |
| SCHEMBL4561971 | 0.73 | CYP3A4 (0.39) | CYP3A4MAPTALDH1A1KDM4ECA2 | |
| SCHEMBL13518528 | 0.69 | CYP3A4 (0.53) | CYP3A4MAPTALDH1A1KDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173803-B2 | Supramolecular scaffolds and methods of making the same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2012-05-08 | — | — | US | disclosed |
| US-8173803-B2 | Supramolecular scaffolds and methods of making the same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2012-05-08 | — | — | US | disclosed |
| US-20100041880-A1 | Supramolecular Scaffolds and Methods of Making the Same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2010-02-18 | — | — | US | disclosed |
| US-20100041880-A1 | Supramolecular Scaffolds and Methods of Making the Same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2010-02-18 | — | — | US | disclosed |
| EP-0576492-A1 | MACROCYCLIC THIOETHER LIGANDS AND THEIR USE AS INTERMEDIATES FOR BINDING IONS TO SUBSTRATES | BRITISH TECHNOLOGY GROUP LTD (GB) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992016520-A1 | MACROCYCLIC THIOETHER LIGANDS AND THEIR USE AS INTERMEDIATES FOR BINDING IONS TO SUBSTRATES | BRITISH TECHNOLOGY GROUP LTD (GB) | 1992-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041880-A1 | Supramolecular Scaffolds and Methods of Making the Same | BLM, TBXAS1, TOP2B | CYP3A4 175/4885MAPT 2040/4885ALDH1A1 1363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.