SCHEMBL456019

SCHEMBL456019

COCc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.62
DRD2 P14416 2/20 0.45
DRD3 P35462 2/20 0.45
DRD4 P21917 1/20 0.45
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PDK2 Q15119 1/20 0.39
HTR2B P41595 2/20 0.37
HTR7 P34969 1/20 0.37
PGR P06401 2/20 0.35
ADRA1A P35348 1/20 0.35
HTR2C P28335 1/20 0.35
MAOA P21397 1/20 0.34
CA1 P00915 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21219200 0.83 PNMT (0.58) PNMTDRD2DRD3DRD4NPC1
SCHEMBL1275883 0.83 PNMT (0.58) PNMTDRD2DRD3DRD4NPC1
SCHEMBL3979804 0.83 PNMT (0.67) PNMTDRD2DRD3DRD4NPC1
SCHEMBL7538016 0.83 PNMT (0.62) PNMTDRD2DRD3DRD4NPC1
SCHEMBL14461656 0.82 PNMT (0.50) PNMTDRD2DRD3DRD4NPC1
SCHEMBL7596847 0.82 PNMT (0.40) PNMTDRD2DRD3DRD4PDK2
SCHEMBL9610281 0.82 PNMT (0.57) PNMTDRD2DRD3DRD4NPC1
SCHEMBL15272778 0.82 PNMT (0.45) PNMTDRD2DRD3DRD4NPC1
SCHEMBL28483707 0.82 PNMT (0.57) PNMTDRD2DRD3DRD4NPC1
SCHEMBL8466215 0.82 PNMT (0.42) PNMTDRD2DRD3DRD4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271748-A DC cable accessory material composition, DC cable accessory material and preparation method thereof 中国石油化工股份有限公司 2024-07-02 CN claimed
CN-117801141-A Catalyst system for olefin polymerization reaction, prepolymerized catalyst composition and application 中国石油化工股份有限公司 2024-04-02 CN claimed
CN-114437264-B Low-VOC low-odor polypropylene resin and preparation method and application thereof 中国石油化工股份有限公司 2024-03-26 CN claimed
CN-112142895-B Application of organosilane, random copolymer polypropylene and preparation method thereof 中国科学院化学研究所 2024-03-22 CN claimed
CN-117683158-A Ultra-clean polypropylene resin and preparation method thereof 中国石油天然气股份有限公司 2024-03-12 CN claimed
WO-2023217945-A1 HETEROPHASIC POLYPROPYLENE COMPOSITION WITH LOW EMISSION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-16 WO claimed
WO-2023217946-A1 HETEROPHASIC POLYPROPYLENE COMPOSITION WITH LOW HEXANE EXTRACTABLES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-16 WO claimed
WO-2023217944-A1 HETEROPHASIC POLYPROPYLENE COMPOSITION WITH LOW SHRINKAGE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-16 WO claimed
CN-115260664-B High-temperature-explosion-resistant polybutene alloy material and preparation method thereof 青岛科技大学 2023-11-03 CN claimed
CN-116769096-A Preparation method of high isotactic polybutene-1 中国石油化工股份有限公司 2023-09-19 CN claimed
WO-2002044219-A1 CATALYST FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2002-06-06 WO claimed
WO-2002012357-A2 METHOD FOR PREPARING A CATALYST SUPPORT FOR α-OLEFIN POLYMERISATION ATOFINA (FR) 2002-02-14 WO claimed
CN-1324886-A Composite nanometer montmorillonoid-polyolefine material and its prepn. CHINESE ACAD INST CHEMISTRY (CN) 2001-12-05 CN claimed
CN-1324869-A Olefine polymerizing catalyst preparing process CHINESE ACAD INST CHEMISTRY (CN) 2001-12-05 CN claimed
CN-1320644-A Process for preparing solid titanium catalyst component used for olefin polymerizing reaction CHINESE ACAD INST CHEMISTRY (CN) 2001-11-07 CN claimed
CN-1313869-A Components and catalysts for the polymerization of olefins BASELL TECHNOLOGY CO B V (NL) 2001-09-19 CN claimed
CN-1298887-A Catalyst system for polymerization or copolymerization of olefine CHINA PETRO CHEM GROUP CORP (CN) 2001-06-13 CN claimed
CN-1287560-A Pre-polymerized catalyst components for the polymerization of olefins MONTELL TECHNOLOGY COMPANY BV (NL) 2001-03-14 CN claimed
CN-1143651-A Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1997-02-26 CN claimed
CN-1141303-A Process for producing solid catalyst component for olefin polymerization MONTELL NORTH AMERICA INC (US) 1997-01-29 CN claimed