Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979804 | 0.83 | PNMT (0.67) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL456019 | 0.83 | PNMT (0.62) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL21359984 | 0.80 | PNMT (0.58) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL1275883 | 0.80 | PNMT (0.58) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7195192 | 0.80 | PNMT (0.72) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL5366733 | 0.80 | PNMT (0.72) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7765 | 0.79 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL22588781 | 0.79 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL31346823 | 0.79 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL1830397 | 0.79 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416730-A1 | DERMATOLOGICAL COSMETIC COMPOSITION COMPRISING AN SDKP PEPTIDE OR AN ANALOG THEREOF | RPM Dermatologie (FR) | 2018-12-26 | — | — | EP | disclosed |
| WO-2002032974-A2 | POLYMER AND ITS USE FOR THE TREATMENT AND/OR PREVENTION OF HYPERPHOSPHOREMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-25 | — | — | WO | disclosed |
| EP-0772451-A4 | TREATMENT OF TYPE II DIABETES MELLITUS WITH AMYLIN AGONISTS | AMYLIN PHARMACEUTICALS INC (US) | 1998-09-30 | — | — | EP | disclosed |
| EP-0772451-A1 | TREATMENT OF TYPE II DIABETES MELLITUS WITH AMYLIN AGONISTS | AMYLIN PHARMACEUTICALS, INC. (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996040220-A1 | TREATMENT OF TYPE II DIABETES MELLITUS WITH AMYLIN AGONISTS | AMYLIN PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0532746-A4 | ASSAY FOR NON-A NON-B HEPATITIS | — | 1993-07-21 | — | — | EP | disclosed |
| EP-0532746-A1 | ASSAY FOR NON-A NON-B HEPATITIS. | BAXTER DIAGNOSTICS INC (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1992017612-A1 | ASSAY FOR NON-A NON-B HEPATITIS | BAXTER DIAGNOSTICS INC. (US) | 1992-10-15 | — | — | WO | disclosed |