SCHEMBL456028

SCHEMBL456028

CCCCOC(=O)CN(O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
NAAA Q02083 1/20 0.52
ATM Q13315 1/20 0.48
DGKA P23743 1/20 0.47
TSHR P16473 2/20 0.45
HPGD P15428 2/20 0.45
RAD52 P43351 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
FAAH O00519 1/20 0.43
DNM1 Q05193 1/20 0.43
HCAR2 Q8TDS4 1/20 0.42
HTR2C P28335 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL452901 0.86 NAAA (0.40) ALDH1A1NAAADGKATSHRRAD52
SCHEMBL2143046 0.83 ALDH1A1 (0.52) ALDH1A1NAAAATMDGKATSHR
SCHEMBL3262568 0.81 ALDH1A1 (0.50) ALDH1A1NAAAATMDGKATSHR
SCHEMBL28214916 0.81 ALDH1A1 (0.50) ALDH1A1NAAAATMDGKATSHR
SCHEMBL338754 0.81 ALDH1A1 (0.50) ALDH1A1NAAAATMDGKATSHR
SCHEMBL28026026 0.81 ALDH1A1 (0.50) ALDH1A1NAAAATMDGKATSHR
SCHEMBL1123507 0.81 ALDH1A1 (0.50) ALDH1A1NAAAATMDGKATSHR
SCHEMBL29163437 0.79 NAAA (0.53) ALDH1A1NAAAATMDGKATSHR
SCHEMBL10664596 0.79 NAAA (0.64) ALDH1A1NAAADGKATSHRRAD52
SCHEMBL30388251 0.78 NAAA (0.57) ALDH1A1NAAAATMDGKATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101421372-A Crosslinking compositions and methods of use thereof DU PONT (US) 2009-04-29 CN claimed
US-9126178-B2 Heat-expandable microspheres and a method of making heat-expandable microspheres and application thereof MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) 2015-09-08 US disclosed
CN-101421373-B Zirconium crosslinking compositions and methods of use DU PONT 2013-04-10 CN disclosed
EP-2529830-A2 Heat-expandable microspheres and a method of making heat-expandable microspheres and application thereof MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) 2012-12-05 EP disclosed
EP-2441814-A1 HEAT-EXPANDABLE MICROSPHERE, METHOD FOR PRODUCING SAME AND USE OF SAME Matsumoto Yushi-Seiyaku Co., Ltd. (JP) 2012-04-18 EP disclosed
US-20120064347-A1 HEAT-EXPANDABLE MICROSPHERES AND A METHOD OF MAKING HEAT-EXPANDABLE MICROSPHERES AND APPLICATION THEREOF MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) 2012-03-15 US disclosed
CN-101421373-A Zirconium crosslinking compositions and methods of use DU PONT (US) 2009-04-29 CN disclosed
CN-101421372-A Crosslinking compositions and methods of use thereof DU PONT (US) 2009-04-29 CN disclosed
CN-100347230-C Water-base composition and crosslinking agent for water-soluble polymers MATSUMOTO CHEMICAL INDUSTRY CO (JP) 2007-11-07 CN disclosed
CN-1606606-A Water-base composition and crosslinking agent for water-soluble polymers MATSUMOTO CHEMICAL INDUSTRY CO (JP) 2005-04-13 CN disclosed