SCHEMBL456030

SCHEMBL456030

CCCCN(O)C(O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.42
FFAR1 O14842 1/20 0.42
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA9 Q16790 2/20 0.39
CA2 P00918 1/20 0.39
MAPK1 P28482 1/20 0.39
KDM5A P29375 3/20 0.37
KDM4C Q9H3R0 2/20 0.37
MAPT P10636 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
LCK P06239 1/20 0.36
PPARD Q03181 1/20 0.36
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
ACHE P22303 1/20 0.35
BACE1 P56817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9791190 0.92 GPR84 (0.48) GPR84FFAR1MAPTLCKPPARD
SCHEMBL452903 0.86 HDAC1 (0.37) GPR84FFAR1CA12CA9CA2
SCHEMBL4913156 0.77
SCHEMBL453464 0.77
SCHEMBL9685476 0.75 TP53 (0.35) GPR84FFAR1
SCHEMBL9791106 0.72 CA2 (0.43) GPR84FFAR1CA1CA2
SCHEMBL6665367 0.72
Lactic Acid SCHEMBL23361679 0.71 TP53 (0.50) GPR84FFAR1CA12CA1CA9
Cadaverine Tartrate SCHEMBL5875373 0.71 KDM5A (0.46) GPR84FFAR1CA12CA1CA9
Cadaverine Tartrate SCHEMBL5875368 0.71 KDM5A (0.46) GPR84FFAR1CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101421372-A Crosslinking compositions and methods of use thereof DU PONT (US) 2009-04-29 CN claimed
US-9126178-B2 Heat-expandable microspheres and a method of making heat-expandable microspheres and application thereof MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) 2015-09-08 US disclosed
CN-102459492-B Thermally expandable microspheres, process for producing thermally expandable microspheres, and use thereof MATSUMOTO YUSHI SEIYAKU KK 2014-11-26 CN disclosed
CN-101421373-B Zirconium crosslinking compositions and methods of use DU PONT 2013-04-10 CN disclosed
EP-2529830-A2 Heat-expandable microspheres and a method of making heat-expandable microspheres and application thereof MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) 2012-12-05 EP disclosed
EP-2441814-A1 HEAT-EXPANDABLE MICROSPHERE, METHOD FOR PRODUCING SAME AND USE OF SAME Matsumoto Yushi-Seiyaku Co., Ltd. (JP) 2012-04-18 EP disclosed
US-20120064347-A1 HEAT-EXPANDABLE MICROSPHERES AND A METHOD OF MAKING HEAT-EXPANDABLE MICROSPHERES AND APPLICATION THEREOF MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) 2012-03-15 US disclosed
CN-101421373-A Zirconium crosslinking compositions and methods of use DU PONT (US) 2009-04-29 CN disclosed
CN-101421372-A Crosslinking compositions and methods of use thereof DU PONT (US) 2009-04-29 CN disclosed
CN-100347230-C Water-base composition and crosslinking agent for water-soluble polymers MATSUMOTO CHEMICAL INDUSTRY CO (JP) 2007-11-07 CN disclosed
CN-1606606-A Water-base composition and crosslinking agent for water-soluble polymers MATSUMOTO CHEMICAL INDUSTRY CO (JP) 2005-04-13 CN disclosed