SCHEMBL4560378

SCHEMBL4560378

C=CCOB(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
AOC3 Q16853 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.33
KCNA3 P22001 1/20 0.32
TSHR P16473 3/20 0.32
LTA4H P09960 1/20 0.32
CASP1 P29466 1/20 0.32
FGFR1 P11362 1/20 0.32
ALOX15 P16050 1/20 0.32
PKM P14618 1/20 0.32
HSD17B10 Q99714 2/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7568394 0.81 CYP3A4 (0.38) CYP3A4ALDH1A1MEN1KMT2AAOC3
Hydrogen Sulfide SCHEMBL27810992 0.79 CYP3A4 (0.37) CYP3A4ALDH1A1MEN1KMT2AAOC3
SCHEMBL9861618 0.72 LTA4H (0.43) KCNA3TSHRLTA4H
SCHEMBL51246 0.72 LTA4H (0.50) ALDH1A1KMT2AKCNA3TSHRLTA4H
SCHEMBL88417 0.72 AOC3 (0.54) ALDH1A1MEN1KMT2AAOC3SMN1; SMN2
SCHEMBL16371575 0.72 AOC3 (0.54) ALDH1A1MEN1KMT2AAOC3SMN1; SMN2
SCHEMBL2143304 0.71 CYP3A4 (0.38) CYP3A4ALDH1A1MEN1KMT2ASMN1; SMN2
Ethylene SCHEMBL15348371 0.71 LTA4H (0.43) ALDH1A1KMT2AKCNA3TSHRLTA4H
SCHEMBL10777066 0.70 LTA4H (0.47) ALDH1A1KMT2AKCNA3TSHRLTA4H
Hydrogen Sulfide SCHEMBL16338972 0.70 LTA4H (0.47) ALDH1A1KMT2AKCNA3TSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090263612-A1 System and Method for Photobleaching of Optical Media NBC UNIVERSAL, INC. (US) 2009-10-22 US disclosed