SCHEMBL7568394

SCHEMBL7568394

C=CCOB(O)Oc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
THRB P10828 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 4/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
PKM P14618 1/20 0.33
CASP1 P29466 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
LIG1 P18858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL27810992 0.98 CYP3A4 (0.37) CYP3A4SMN1; SMN2MEN1KMT2ATHRB
SCHEMBL4560378 0.81 CYP3A4 (0.36) CYP3A4SMN1; SMN2MEN1KMT2ATHRB
SCHEMBL15544573 0.76 ALDH1A1 (0.40) MEN1KMT2AALDH1A1TSHRCA1
SCHEMBL28835309 0.75 CHRNB2 (0.37) CYP3A4SMN1; SMN2KDM4EALDH1A1TSHR
SCHEMBL1878004 0.75 CA1 (0.46) ALDH1A1TSHRCA1CA2RECQL
SCHEMBL28682860 0.75 CA1 (0.36) ALDH1A1TSHRCA1CA2RECQL
SCHEMBL27607789 0.75 TAAR1 (0.39) CYP3A4MEN1KMT2ATHRBKDM4E
Boric Acid SCHEMBL28533478 0.75 AOC3 (0.47) SMN1; SMN2MEN1KMT2ATHRBKDM4E
SCHEMBL2126537 0.75 LTA4H (0.41) SMN1; SMN2ALDH1A1TSHRCA1CA2
SCHEMBL3395239 0.75 CA1 (0.36) SMN1; SMN2MEN1KMT2ATHRBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2054454-B1 REACTIVE NEAR INFRARED ABSORBING POLYMERIC PARTICLES, METHODS OF PREPARATION AND USES THEREOF AMERICAN DYE SOURCE INC (CA) 2017-11-08 EP claimed
CN-105714265-A Preparation method of boron-doped graphene film 中国科学院上海高等研究院 2016-06-29 CN claimed
CN-116710438-A Method and system for producing furfural 国际壳牌研究有限公司 2023-09-05 CN disclosed
CN-116529236-A Method and system for producing furfural 国际壳牌研究有限公司 2023-08-01 CN disclosed
CN-105714265-A Preparation method of boron-doped graphene film 中国科学院上海高等研究院 2016-06-29 CN disclosed
EP-0846119-B1 THIENOPYRIMIDINE DERIVATIVES, THEIR PRODUCTION AND USE AS ENDOTHELIN ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-11-13 EP disclosed
EP-0781774-B1 Prolactin production inhibitory agents TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-07-31 EP disclosed
US-6140325-A HAS ENDOTHELIN ANTAGONISTIC ACTION; FOR TREATING LIVER HYPOFUNCTION, ACUTE RENAL INSUFFICIENCY, CARDIAC INFARCTION OR LIVER INSUFFICIENCY, VASOCONSTRICTION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-10-31 US disclosed
US-6015789-A LUTEINIZING HORMONE RELEASING HORMONE AGONIST AND A LUTEINIZING HORMONE RELEASING HORMONE ANTAGONIST IN COMBINATION, TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-01-18 US disclosed
US-5977132-A GALACTORRHEA, HYPERPROLACTINEMIC OVULATION, PROLACTINOMA AND BRAIN TUMORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-11-02 US disclosed
EP-0906115-A1 COMBINED USE OF GnRH AGONIST AND ANTAGONIST Takeda Chemical Industries, Ltd. (JP) 1999-04-07 EP disclosed
EP-0846119-A1 THIENOPYRIMIDINE DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1998-06-10 EP disclosed
WO-1997040846-A1 COMBINED USE OF GnRH AGONIST AND ANTAGONIST TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-11-06 WO disclosed
EP-0781774-A2 Prolactin production inhibitory agents TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-07-02 EP disclosed
WO-1997007119-A1 THIENOPYRIMIDINE DERIVATIVES, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-02-27 WO disclosed