⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250687 | 0.89 | DAO (0.50) | — | |
| Phenol SCHEMBL17456368 | 0.71 | L3MBTL1 (0.50) | — | |
| SCHEMBL1503 | 0.71 | — | — | |
| SCHEMBL220072 | 0.70 | — | — | |
| SCHEMBL30404482 | 0.69 | — | — | |
| Potassium SCHEMBL30471622 | 0.69 | — | — | |
| SCHEMBL29150915 | 0.69 | — | — | |
| SCHEMBL28959328 | 0.69 | HCAR2 (0.44) | — | |
| SCHEMBL30802139 | 0.69 | — | — | |
| SCHEMBL28852463 | 0.69 | HCAR2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56169673-A | — | — | None | — | — | JP | disclosed |
| JP-56169674-A | — | — | None | — | — | JP | disclosed |
| EP-4642535-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS SIK MODULATORS | F. Hoffmann-La Roche AG (CH) | 2025-11-05 | — | — | EP | disclosed |
| EP-4562015-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| EP-4547662-A1 | IMIDAZO[4,5-B]PYRIDINE AND PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES AS SIK MODULATORS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS | F. Hoffmann-La Roche AG (CH) | 2025-05-07 | — | — | EP | disclosed |
| US-20250127780-A1 | IMIDAZO[4,5-B]PYRIDINE AND PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES AS SIK MODULATORS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS | HOFFMANN-LA ROCHE INC. (US) | 2025-04-24 | — | — | US | disclosed |
| CN-113135896-B | Methylpyrazole derivatives as RET inhibitors | 正大天晴药业集团股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-114984003-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2024-08-27 | — | — | CN | disclosed |
| WO-2024141443-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS SIK MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-04 | — | — | WO | disclosed |
| CN-115054600-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2024-06-14 | — | — | CN | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
| WO-2005023247-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-03-17 | — | — | WO | disclosed |
| EP-1377556-A1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | Pfizer Limited (GB) | 2004-01-07 | — | — | EP | disclosed |
| EP-1362852-A1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-20030100554-A1 | Pyrazole derivatives | JONES LYN HOWARD (GB) | 2003-05-29 | — | — | US | disclosed |
| WO-2002085860-A1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | PFIZER LIMITED (GB) | 2002-10-31 | — | — | WO | disclosed |
| EP-0636121-A1 | ARTHROPODICIDAL PYRAZOLE SULFONATES | Dunlena Pty. Limited (AU) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021160-A1 | ARTHROPODICIDAL PYRAZOLE SULFONATES | DUNLENA PTY. LTD. (AU) | 1993-10-28 | — | — | WO | disclosed |
| JP-S56169674-A | PREPARATION OF 1-SUBSTITUTED-4-BENZOYL-5-HYDROXY-3- METHYLPYRAZOLE DERIVATIVE | SANKYO CO LTD | 1981-12-26 | — | — | JP | disclosed |
| JP-S56169673-A | 4-BENZOYLPYRAZOLE DERIVATIVE | SANKYO CO LTD | 1981-12-26 | — | — | JP | disclosed |