Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5944409 | 0.94 | KDM4E (0.41) | KMT2AMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4562150 | 0.94 | KMT2A (0.40) | TOP1KMT2AMAPTNPSR1MEN1 | |
| SCHEMBL4562438 | 0.93 | RAB9A (0.42) | TOP1KMT2AMAPTCYP2C19MEN1 | |
| SCHEMBL5944241 | 0.93 | PRKCQ (0.35) | TOP1KMT2AMAPTMEN1MKNK1 | |
| SCHEMBL4561407 | 0.93 | KDM4E (0.39) | KMT2AMAPTCYP1A2CYP2C19NPSR1 | |
| SCHEMBL4562434 | 0.92 | MAPT (0.36) | TOP1KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL4561484 | 0.92 | MAPT (0.36) | TOP1KMT2AMAPTMEN1RAB9A | |
| SCHEMBL5944422 | 0.91 | PDE4A (0.37) | KMT2ARAB9AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL4562395 | 0.91 | TOP1 (0.43) | TOP1KMT2AMAPTCYP2C9MEN1 | |
| SCHEMBL2693505 | 0.91 | KDM4E (0.42) | KMT2AMAPTCYP1A2CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722209-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722209-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-11-29 | — | — | US | disclosed |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-11-29 | — | — | US | disclosed |
| EP-2457912-A1 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | Hodogaya Chemical Co., Ltd. (JP) | 2012-05-30 | — | — | EP | disclosed |
| EP-2053051-B1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO LTD (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-8168308-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8168308-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2053051-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2009-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | SCO2, PNPO, WEE1 | TOP1 1941/4885KMT2A 966/4885MAPT 3416/4885 |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | PNPO, SCO2, OR10J3 | TOP1 2013/4885KMT2A 1978/4885MAPT 3595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.