Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4561428 | 0.94 | TOP1 (0.35) | KDM4ETP53SMN1; SMN2LMNAALPL | |
| SCHEMBL4562144 | 0.93 | KDM4E (0.40) | KDM4ETP53SMN1; SMN2LMNAALPL | |
| SCHEMBL4562150 | 0.93 | KMT2A (0.40) | KDM4ETP53SMN1; SMN2LMNAALPL | |
| SCHEMBL4562438 | 0.92 | RAB9A (0.42) | KDM4ETP53SMN1; SMN2LMNAALPL | |
| SCHEMBL4562434 | 0.91 | MAPT (0.36) | KDM4ETP53SMN1; SMN2LMNAALPL | |
| SCHEMBL2693505 | 0.91 | KDM4E (0.42) | KDM4ETP53SMN1; SMN2LMNAALPL | |
| SCHEMBL4562395 | 0.90 | TOP1 (0.43) | LMNAMAPTKMT2ACYP2C9MAPK14 | |
| SCHEMBL5944422 | 0.90 | PDE4A (0.37) | KDM4ETP53SMN1; SMN2LMNAALPL | |
| SCHEMBL4561407 | 0.89 | KDM4E (0.39) | KDM4ETP53SMN1; SMN2LMNAALPL | |
| SCHEMBL15706680 | 0.88 | HTR1A (0.33) | KDM4ETP53SMN1; SMN2LMNAALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722209-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722209-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-11-29 | — | — | US | disclosed |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-11-29 | — | — | US | disclosed |
| EP-2457912-A1 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | Hodogaya Chemical Co., Ltd. (JP) | 2012-05-30 | — | — | EP | disclosed |
| EP-2053051-B1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO LTD (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-8168308-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8168308-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2053051-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2009-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | SCO2, PNPO, WEE1 | KDM4E 690/4885TP53 4217/4885SMN1; SMN2 3613/4885 |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | PNPO, SCO2, OR10J3 | KDM4E 1532/4885TP53 4146/4885SMN1; SMN2 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.